Method for determining analytes in body fluids and also a new implantable measurement device
First Claim
1. A diagnostic apparatus for determining analytes in body liquids, which comprises(i) at least one measurement unit for single or continuous determination of an analyte, wherein the measurement unit contains at least one measurement chamber and generates a signal in the presence of the analyte to be determined and wherein the measurement chamber(s) contain(s) photosensitizers;
- (ii) at least one signal transmission unit capable of converting the signal and forwarding it to a signal-processing unit or capable of forwarding the unconverted signal to a signal-processing unit; and
(iii) at least one sample feeder to each measurement unit which is adapted to extend into the relevant liquid-containing body compartment.
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Abstract
The present invention relates to an implantable diagnostic apparatus for determining analytes in body fluids, which comprises a plurality of identical and/or different measurement units for determining an analytic parameter, in which a signal is generated which is specifically related to the variable to be determined and is transmitted by means of suitable measures to a receiver situated outside the body.
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Citations
18 Claims
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1. A diagnostic apparatus for determining analytes in body liquids, which comprises
(i) at least one measurement unit for single or continuous determination of an analyte, wherein the measurement unit contains at least one measurement chamber and generates a signal in the presence of the analyte to be determined and wherein the measurement chamber(s) contain(s) photosensitizers; -
(ii) at least one signal transmission unit capable of converting the signal and forwarding it to a signal-processing unit or capable of forwarding the unconverted signal to a signal-processing unit; and
(iii) at least one sample feeder to each measurement unit which is adapted to extend into the relevant liquid-containing body compartment. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18)
(a) reacting the analytes with photosensitizers in such a way that the photosensitizers yield, depending on the analyte'"'"'s concentration or activity, singlet oxygen;
(b) measuring said singlet oxygen;
(c and converting said measurements into a transmittable signal.
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17. A method for determining analytes or their activity using a diagnostic apparatus as claimed in claim 1, the method comprising the steps of:
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(a) generating a signal in the presence of analytes with photosensitizers that are in close proximity with acceptors;
(b) activating said acceptors with singlet oxygen generated by said photosensitizers which subsequently produce light;
(c) and detecting said light.
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18. A method according to claims 16 or 17 used for the detection of hemostasis disturbances.
Specification