Monitoring of myocardial revascularization
First Claim
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1. Apparatus for PMR treatment, comprising:
- an elongate probe having a distal end for engaging heart tissue of a subject, and comprising a revascularization device, which imparts energy to the heart tissue for generating perfusion-enhancing channels therein; and
a sensor, which provides an indication responsive to the treatment wherein the sensor comprises a blood flow sensor, which generate signals responsive to microcirculation.
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Abstract
Apparatus for PNR treatment, including an elongate probe having a distal end for engaging heart tissue of a subject, and a revascularization device, which imparts energy to the heart tissue for generating perfusion-enhancing channels therein. A sensor provides an indication responsive to the treatment, preferably by receiving signals generated by the body of the subject.
72 Citations
22 Claims
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1. Apparatus for PMR treatment, comprising:
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an elongate probe having a distal end for engaging heart tissue of a subject, and comprising a revascularization device, which imparts energy to the heart tissue for generating perfusion-enhancing channels therein; and
a sensor, which provides an indication responsive to the treatment wherein the sensor comprises a blood flow sensor, which generate signals responsive to microcirculation. - View Dependent Claims (2)
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3. Apparatus for PMR treatment, comprising:
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an elongate probe having a distal end for engaging heart tissue of a subject, and comprising a revascularization device, which imparts energy to the heart tissue for generating perfusion-enhancing channels therein;
a sensor, which provides an indication responsive to the treatment; and
signal processing circuitry, which is coupled to the sensor and analyzes the signals to provide an indication of the efficacy of the treatment, wherein the circuitry detects an elevated ST segment. - View Dependent Claims (4, 5, 6, 7, 8, 9, 10, 11)
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12. A method for monitored PMR treatment of the heart of a subject, comprising:
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bringing a probe, including a revascularization device for imparting energy to the heart, into engagement with heart tissue of a subject;
imparting energy to the heart tissue using the device so as to generate perfusion-enhancing channels therein;
transmitting fluorescence-stimulating radiation to the heart tissue through an optical waveguide; and
receiving a signal from the body of the subject responsive to the treatment by receiving energy reflected from the heart tissue by receiving fluorescence radiation emitted from the heart tissue through a light detector. - View Dependent Claims (13, 14)
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15. A method for monitored PMR treatment of the heart of a subject, comprising:
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bringing a probe, including a revascularization device for imparting energy to the heart, into engagement with heart tissue of a subject;
imparting energy to the heart tissue using the device so as to generate perfusion-enhancing channels therein;
receiving a signal from the body of the subject responsive to the treatment; and
processing the signal to provide an indication of the efficacy of the treatment by detecting an elevated ST segment. - View Dependent Claims (16, 17, 18, 19)
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20. Apparatus for PMR treatment, comprising:
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an elongate probe having a distal end for engaging heart tissue of a subject, and comprising a revascularization device, which imparts energy to the heart tissue for generating perfusion-enhancing channels therein;
a sensor, which provides an indication responsive to the treatment; and
signal processing circuitry, which is coupled to the sensor and analyzes the signals to provide an indication of the efficacy of the treatment, wherein the circuitry detects an arrhythmia, and wherein the arrhythmia detected by the circuitry comprises at least one VPB.
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21. A method for monitored PMR treatment of the heart of a subject, comprising:
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bringing a probe, including a revascularization device for imparting energy to the heart, into engagement with heart tissue of a subject;
imparting energy to the heart tissue using the device so as to generate perfusion-enhancing channels therein; and
receiving a signal from the body of the subject responsive to the treatment by receiving signals responsive to microcirculation blood flow rate adjacent a designated channel location within the heart.
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22. A method for monitored PMR treatment of the heart of a subject, comprising:
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bringing a probe, including a revascularization device for imparting energy to the heart, into engagement with heart tissue of a subject;
imparting energy to the heart tissue using the device so as to generate perfusion-enhancing channels therein;
receiving a signal from the body of the subject responsive to the treatment; and
processing the signal to provide an indication of the efficacy of the treatment by detecting an arrhythmia through detecting a VPB.
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Specification