Low attenuation guide wire for intravascular radiation delivery
First Claim
1. A guide wire for use in intravascular ionizing radiation therapy, comprising an elongate shaft having a proximal region and a distal region, the distal region being less attenuating to ionizing radiation than the proximal region.
1 Assignment
0 Petitions
Accused Products
Abstract
A low attenuation guide wire for use in combination with a radiation device for intravascular ionizing radiation therapy. The distal region of the guide wire is less attenuating to ionizing radiation than the proximal region and may be disposed adjacent the radiation emitting portion of the radiation device without significantly compromising the emission of radiation. Thus, the guide wire does not need to be removed or retracted in order to effectively deliver ionizing radiation to the vascular target site.
262 Citations
46 Claims
-
1. A guide wire for use in intravascular ionizing radiation therapy, comprising an elongate shaft having a proximal region and a distal region, the distal region being less attenuating to ionizing radiation than the proximal region.
- 2. A guide wire for use in intravascular ionizing radiation therapy, comprising an elongate shaft having a proximal region and a distal region, wherein the distal region includes a proximal end portion and a distal end portion, the proximal end portion being relatively less attenuating to ionizing radiation, and the distal end portion being relatively more radiopaque.
-
31. A system for administering intravascular ionizing radiation therapy, comprising:
-
an intravascular device having a distal portion emitting ionizing radiation; and
a guide wire comprising an elongate shaft having a proximal region and a distal region, the distal region being less attenuating to ionizing radiation than the proximal region, the distal region being disposed adjacent the distal portion of the intravascular device. - View Dependent Claims (32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42)
-
-
43. A guide wire for use in intravascular ionizing radiation therapy, comprising an elongate shaft having a proximal portion, a mid portion and a distal portion, the mid portion being less attenuating to ionizing radiation than the proximal and distal portions, and the distal portion being more radiopaque than the mid portion.
-
44. A method of administering intravascular ionizing radiation therapy to a treatment site in a patient'"'"'s vascular system, the method comprising the steps of:
-
providing an intravascular device having a distal portion emitting ionizing radiation;
providing a guide wire comprising an elongate shaft having a proximal region and a distal region, the distal region being less attenuating to ionizing radiation than the proximal region;
advancing the guide wire through the patient'"'"'s vascular system until the distal region is disposed adjacent the treatment site; and
advancing the intravascular device through the patient'"'"'s vascular system until the distal portion emitting ionizing radiation is disposed adjacent the treatment site whereby radiation emitted from the distal portion of the intravascular device traverses the less attenuating distal region of the guide wire. - View Dependent Claims (45, 46)
-
Specification