Dietary supplement and method for use as a probiotic, for alleviating the symptons associated with irritable bowel syndrome

• US 6,203,797 B1
• Filed: 01/07/2000
• Issued: 03/20/2001
• Est. Priority Date: 01/06/1998
• Status: Expired due to Term

• Current Assignee: Stephen C. Perry
• Original Assignee: Stephen C. Perry
• Inventors: Perry, Stephen C.
• Primary Examiner(s): Lilling, Herbert J.
• Application Number:
  US09/479,164
• Time in Patent Office: 438 Days
• Field of Search: 424/195.1, 435/101
• US Class Current: 424/93.45
• CPC Class Codes: A23L 29/065 Microorganisms addition of bacteria for nutritional purposes A23L33/135
• CPC Class Codes: A23L 29/244 from corms, tubers or roots, e.g. glucomannan starch A23L29/212
• CPC Class Codes: A23L 33/105 Plant extracts, their artificial duplicates or their derivatives
• CPC Class Codes: A23V 2002/00 Food compositions, function of food ingredients or processes for food or foodstuffs
• CPC Class Codes: A23V 2250/062 Glutamine
• CPC Class Codes: A23V 2250/1612 Manganese
• CPC Class Codes: A23V 2250/2102 Aloe
• CPC Class Codes: A23V 2250/5062 Inulin
• CPC Class Codes: A23V 2250/7052 Vitamin B6
• CPC Class Codes: A61K 2300/00 Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
• CPC Class Codes: A61K 31/198 Alpha-amino acids, e.g. alanine or edetic acid [EDTA] betaine A61K31/205; proline A61K31/401; tryptophan A61K31/405; histidine A61K31/4172; peptides not degraded to individual amino acids A61K38/00
• CPC Class Codes: A61K 31/4415 Pyridoxine, i.e. Vitamin B6 pyridoxal phosphate A61K31/675
• CPC Class Codes: A61K 31/702 Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
• CPC Class Codes: A61K 31/715 Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
• CPC Class Codes: A61K 33/32 Manganese; Compounds thereof
• CPC Class Codes: A61K 36/28 Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
• CPC Class Codes: A61K 36/886 Aloeaceae (Aloe family), e.g. aloe vera
• CPC Class Codes: A61K 38/4873 Cysteine endopeptidases (3.4.22), e.g. stem bromelain, papain, ficin, cathepsin H
• CPC Class Codes: C12Y 304/22001 Cathepsin B (3.4.22.1)
• CPC Class Codes: C12Y 304/22004 Bromelain (3.4.22.4) C12Y304/22032, C12Y304/22033 take precedence

Abstract

A dietary supplement for use as a probiotic and for alleviating symptoms of irritable bowel syndrome, comprising freeze-dried aloe, fructo-oligosaccharides, and dahlia inulin juice mixture and optionally vitamin B6 (pyridoxine) manganese and L-glutamine. An additional alternate embodiments specifically for alleviation of symptoms of irritable bowel syndrome, including in the base formula bromelain and papain. Also for specific probiotic functions the following friendly bacteria: Lactobacillus bulgaricus, lactobacillus acidophilus, lactobacillus plantarum, and Bifidobacterium bifidum could be added to the base formula.

Claims

1. A dietary supplement for use as a probiotic and for alleviating the symptoms associated with irritable bowel syndrome, comprising the following ingredients by weight:

freeze-dried Aloe Vera Linne plant, 25-200 parts;

vitamin B6 (pyridoxine hydrochloride), 10-100 parts;

manganese, 30-150 parts;

L-Glutamine, 150-300 parts;

fructo-oligosaccharides, 100-200 parts, and in addition thereto,

dahlia inulin juice mixture, 25-200 parts.

2. A dietary supplement as in claim 1, specifically for alleviating the symptoms of irritable bowel syndrome, further comprising the following ingredients by weight:

bromelain, 35-160 parts; and

papain, 50-170 parts.

3. A dietary supplement as in claim 2, for use as a probiotic and to alleviate the symptoms of irritable bowel syndrome, further comprising:

Lactobacillus bulgaricus, 500,000,000 CFU;

Lactobacillus acidophilus, 500,000,000 CFU;

Lactobacillus plantarum, 500,000,000 CFU; and

Bifidobacterium bifidum, 500,000,000 CFU.

4. A dietary supplement for use as a probiotic as in claim 2, wherein said freeze-dried Aloe Vera Linne is made by the process of homogenizing entire leaves of the plant, vacuum freeze-drying the homogenate, granulating the vacuum freeze-dried mass and compacting the resulting granules into tablets.

5. The method of alleviating the symptoms of irritable bowel syndrome and for use as a probiotic in the body of a mammal to be treated comprising the step of daily oral administration to said mammal of the dietary supplement mixture comprising by weight (a) 25-220 parts freeze dried Aloe Vera Linne Plant;

(b) 100-200 parts fructo-oligosaccharides;

(c) 25-200 parts dahlia inulin juice mixture in addition to (b);

(d) 10-100 parts vitamin B6;

(e) 30-150 parts manganese; and

(f) 150-300 parts L-Glutamine in amounts effective to alleviate the symptoms of irritable bowel syndrome and for use as a probiotic.

6. The method of claim 5 further comprising by weight:

bromelain 35-150 parts; and

papain, 50-170 parts.

7. The method of claim 6 wherein said dietary composition further comprises by weight at least 500,000,000 CFU of one type of beneficial human intestinal microorganism selected from the group consisting of Lactobacillus bulgaricus, L. acidophilus, L. plantarum, and Bifidobacterium bididum or a combination thereof.