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Transgenic non-human mammals expressing heterologous glycosyltransferase DNA sequences produce oligosaccharides and glycoproteins in their milk

  • US 6,204,431 B1
  • Filed: 09/05/1997
  • Issued: 03/20/2001
  • Est. Priority Date: 03/09/1994
  • Status: Expired due to Fees
First Claim
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1. A non-human, transgenic mammal, wherein the genome of said mammal comprises at least one heterologous DNA sequence encoding an enzyme, wherein said enzyme is a glycosyltransferase operatively linked to a mammary gland-specific promoter, wherein expression of said at least one DNA sequence results in the production of oligosaccharides and glycoproteins in the milk of said mammal.

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