Ultrasound-guided ablation catheter and methods of use

• US 6,206,831 B1
• Filed: 01/06/1999
• Issued: 03/27/2001
• Est. Priority Date: 01/06/1999
• Status: Expired due to Fees

• Current Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Original Assignee: Scimed Life Systems Incorporated (Boston Scientific Corporation)
• Inventors: Panescu, Dorin, Swanson, David K., TenHoff, Harm, Whayne, James G., Suorsa, Veijo T.
• Primary Examiner(s): COHEN, LEE S
• Application Number:
  US09/227,281
• Time in Patent Office: 811 Days
• Field of Search: 600/439, 600/467, 600/374, 606/41, 607/99, 607/113, 607/122, 601/2
• US Class Current: 600/439
• CPC Class Codes: A61B 18/1492 having a flexible, catheter-like structure, e.g. for heart ablation A61B18/1477 takes precedence
• CPC Class Codes: A61B 2017/00106 ultrasonic
• CPC Class Codes: A61B 2018/0016 Energy applicators arranged in a two- or three dimensional array
• CPC Class Codes: A61B 2018/00351 Heart
• CPC Class Codes: A61B 2018/00577 Ablation
• CPC Class Codes: A61B 2018/00654 with individual control of each of a plurality of energy emitting elements
• CPC Class Codes: A61B 2018/124 switching the output to different electrodes, e.g. sequentially
• CPC Class Codes: A61B 2090/065 for measuring contact or contact pressure
• CPC Class Codes: A61B 2090/3784 both receiver and transmitter being in the instrument or receiver being also transmitter
• CPC Class Codes: A61N 2007/0078 with multiple treatment transducers
• CPC Class Codes: A61N 7/02 Localised ultrasound hyperthermia hyperthermia in general A61F7/00

Abstract

The present invention provides ultrasound-guided ablation catheters and methods for their use. In one embodiment, a tissue ablation apparatus (2) includes a flexible elongate body (12) having proximal (14) and distal (12) ends. A plurality of spaced-apart electrodes (24) are operably attached to the flexible body near the distal end. A plurality of transducer elements (28) are disposed between at least some of the electrodes. Transducers assist the physician in determining whether or not the ablation elements are in contact with the tissue to be ablated.

Claims

1. A tissue ablation apparatus, comprising:

a flexible elongate body having a proximal end and a distal end;

a plurality of spaced apart electrodes operably attached to said flexible body near said distal end; and

a plurality of transducer elements disposed between at least some of said electrodes;

wherein said electrodes and said transducer elements are operably attached to said flexible body in an alternating fashion; and

wherein the number of said transducer elements exceeds the number of said electrodes by at least one.

2. A tissue ablation apparatus as in claim 1, wherein each electrode has at least one transducer element adjacent thereto.

3. A tissue ablation apparatus as in claim 1, further comprising a plurality of insulators operably attached to said flexible body to insulate said transducer elements from said electrodes.

4. A tissue ablation apparatus as in claim 1, wherein said flexible body has an outer diameter that is less than about eight French.

5. A tissue ablation apparatus as in claim 1, wherein said electrodes are spaced apart from adjacent said electrodes by a gap, said gap being between about 1.5 millimeters and about 3.0 millimeters.

6. A tissue ablation apparatus as in claim 5, wherein one of said plurality of transducer elements is operably attached to said body in each said gap.

7. A tissue ablation apparatus as in claim 1, wherein said transducer elements comprise cylindrical transducer elements, said elements each having a throughhole, and wherein said elements are positioned so that a longitudinal axis of said flexible body passes through said throughholes.

8. A tissue ablation apparatus as in claim 1, wherein said electrodes comprise generally cylindrical electrodes each having an inner surface and an outer surface, said electrodes being positioned so that said inner surfaces face a longitudinal axis of said flexible body.

9. A tissue ablation apparatus as in claim 1, wherein said apparatus comprises between about two and about fourteen electrodes, and between about three and about fifteen transducer elements.

10. A tissue ablation apparatus as in claim 1, wherein said electrodes and said transducer elements are adapted to be connected to a controller.

11. A tissue ablation apparatus as in claim 1, further comprising a thermocouple operably attached to said flexible body.

12. The apparatus of claim 1 further comprising a controller in electrical communication with said plurality of transducer elements and said plurality of electrodes.

13. An apparatus as in claim 12, wherein said controller comprises an ultrasound imaging and ablation controller.

14. An apparatus as in claim 12, further comprising a plurality of leads, wherein at least one lead is operably attached to each of said transducer elements.

15. An apparatus as in claim 14, wherein said plurality of leads are in electrical communication with said controller to allow a plurality of electrical signals to be sent by said controller to said transducer elements.

16. An apparatus as in claim 14, further comprising a multiplexer operably attached to said flexible body and in electrical communication with said controller, and wherein at least some of said leads are operably attached to said multiplexer.

17. A method of ablating tissue comprising:

providing a tissue ablation apparatus, said apparatus comprising a flexible elongate body, a plurality of electrodes and a plurality of transducer elements, said electrodes and said transducer elements being operably attached to said body in an alternating fashion so that said electrodes each have at least one of said plurality of transducer elements located distal thereto and at least one of said plurality of transducer elements located proximal thereto, said electrodes and said transducer elements being in electrical communication with a controller;

inserting said ablation apparatus into a patient;

positioning said ablation apparatus within said patient so that said ablation apparatus is proximate a tissue to be ablated;

energizing said transducer elements;

receiving a plurality of reflected signals from said transducer elements;

processing said reflected signals with said controller to determine if said transducer elements are in contact with said tissue to be ablated; and

activating at least one of said electrodes to ablate said tissue if said controller determines that said transducer elements adjacent to said at least one electrode in the proximal and distal directions are in contact with said tissue.

18. A method as in claim 17, further comprising processing said reflected signals to determine if all of said transducer elements are in contact with said tissue prior to said activating step.

19. A method as in claim 17, further comprising repositioning said ablation apparatus if said controller determines that at least one of said transducer elements is not in contact with said tissue.

20. A method as in claim 17, wherein said ablation apparatus further comprises a multiplexer operably attached to said body and in electrical communication with said transducer elements, said multiplexer for coordinating the order in which said transducers are energized by said energizing step.

21. The method of claim 17 wherein said apparatus comprises between about two and about fourteen electrodes, and between about three and about fifteen transducer elements.

22. The method of claim 17 wherein the number of transducer elements exceeds the number of electrodes by at least one.

23. The method of claim 17 wherein each of said electrodes except a distal-most electrode and a proximal-most electrode, has one transducer element separating said electrode from an adjoining electrode in the distal direction and one transducer element separating said electrode from an adjoining electrode in the proximal direction.