Macrocyclic compounds having nitrogen-containing linkages
First Claim
1. A compound of the structure:
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whereinX is (—
T—
L)y y is 0-3 each T is, independently, a single bond, a methylene group or a group having the structure
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Abstract
Novel macrocyclic compounds are constructed to include a ring or ring system having two bridgehead atoms with a bridge extending between the bridgehead atoms. Located in at least the bridge are two or more nitrogenous moieties that are derivatized with chemical functional groups. The ring or ring systems can include further nitrogenous moieties, either as ring atoms or on pendant groups attached to the ring. These can also be derivatized with chemical functional groups. The totality of the chemical functional groups imparts certain conformational and other properties to the compounds. In accordance with certain embodiments of the invention, libraries of such compounds are prepared utilizing permutations and combinations of the chemical functional groups and the nitrogenous moieties to build complexity into the library.
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Citations
6 Claims
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1. A compound of the structure:
-
wherein X is (—
T—
L)yy is 0-3 each T is, independently, a single bond, a methylene group or a group having the structure - View Dependent Claims (2, 3, 4, 5, 6)
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Specification