Electroporation apparatus with connective electrode template
First Claim
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1. An electrode template apparatus for use in electroporation, comprising:
- a primary support member having opposite surfaces;
a plurality of bores extending through said support member and through said opposite surfaces;
a plurality of conductors on separate levels of said support member between said opposite surfaces and each separately connected to at least one of said plurality of bores;
a plurality of electrodes selectively insertable in said plurality of bores so that each conductor is connected to at least one electrode; and
means for connecting said conductors to a power supply.
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Abstract
An electrode template apparatus, includes a three dimensional support member having opposite surfaces, a plurality of bores extending through the support member and through the opposite surfaces, a plurality of conductors on the member separately connected to the plurality of bores, a plurality of needle electrodes selectively extendable through the plurality of bores and into tissue to be electroporated so that each electrode is comcected to at least one conductor for connecting the electrodes to a power supply.
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Citations
30 Claims
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1. An electrode template apparatus for use in electroporation, comprising:
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a primary support member having opposite surfaces;
a plurality of bores extending through said support member and through said opposite surfaces;
a plurality of conductors on separate levels of said support member between said opposite surfaces and each separately connected to at least one of said plurality of bores;
a plurality of electrodes selectively insertable in said plurality of bores so that each conductor is connected to at least one electrode; and
means for connecting said conductors to a power supply. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18)
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19. An electrode template apparatus for use in electroporation, comprising:
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a primary support member comprising a multi-layer printed circuit board having opposite surfaces;
a plurality of aligned bores extending through said board and through said opposite surfaces;
a conductor on each layer connected to a plurality of the bores on the board;
a plurality of electrodes selectively insertable in said plurality of bores so that each conductor is connected to at least one electrode; and
means for connecting said conductors to a power supply. - View Dependent Claims (20, 21, 22, 23)
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24. An electrode template apparatus for use in electroporation, comprising:
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a primary support member having opposite surfaces;
a plurality of bores extending through said support member and through said opposite surfaces;
a plurality of conductors on said support member and separately connected to at least one of said plurality bores;
a moveable support member is mounted for movement toward and away from said primary support member;
a plurality of electrodes mounted on said moveable support member and slideably mounted in said plurality of bores so that each conductor is connected to at least one electrode, wherein one of said moveable support member and said primary support member is tubular and the other of said moveable support member and said primary support member is telescopically mounted for movement in said one of said support members and wherein said support members are disposed on an end of a catcher; and
means for connecting said conductors to a power supply.
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25. A needle electrode template apparatus for use in electroporation, comprising:
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a primary support member having a plurality of support surfaces between opposite parallel surfaces;
a plurality of bores arranged in an array of parallel rows and extending through said support member and through said opposite surfaces;
a plurality of conductors on each of said plurality of support surfaces separately connected to at least one of said plurality of bores;
a plurality of needle electrodes adapted to be selectively mounted in said plurality of bores so that each conductor may be connected to at least one electrode;
at least one of said needle electrodes having a tubular configuration for injection of molecules into tissue and means for connecting said conductors to a power supply. - View Dependent Claims (26)
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27. A needle electrode template apparatus for use in electroporation, comprising:
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a primary support member having opposite parallel surfaces;
a plurality of bores arranged in a rectangular any and extending through said support member and through said opposite surfaces;
a plurality of bores arranged in a rectangular array and extending through said support member and through said opposite surfaces;
a plurality of conductors on said support member separately connected to at least one of said plurality of bores;
a plurality of electrodes mounted on said moveable support member and slideably mounted in said plurality of bores so that each conductor is connected to at least one electrode, wherein one of said moveable support member and said primary support member is tubular and the other of said moveable support member and said primary support member is telescopically mounted for movement in said one of said support members, at least one of said needle electrodes having a tubular configuration for injection of molecules into tissue and wherein said support members are disposed on an end of a catheter.
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28. An electrode template apparatus for use in electroporation, comprising:
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a primary support member comprising multiple printed circuit boards and having opposite surfaces;
a plurality of aligned bores extending through said boards; and
a plurality of conductors on each board separately connected to at least one of said plurality of the bores;
a plurality of electrodes selectively insertable in said plurality of bores so that each conductor is connected to at least one electrode; and
means for connecting said conductors to a power supply. - View Dependent Claims (29, 30)
said plurality of bores are disposed in a plurality of parallel rows; and
switching means for selectively connecting said conductors to a power supply so that multiple needle electrodes of one plurality oppose multiple needles of an opposite polarity.
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30. An electrode apparatus according to claim 29 wherein:
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said plurality of parallel rows are at least two in number in each direction; and
switching means is operative for selectively connecting said conductors to a power supply so that all parallel rows of needle electrodes in a given direction are simultaneously pulsed.
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Specification