Thermotherapy probe

• US 6,216,041 B1
• Filed: 07/22/1997
• Issued: 04/10/2001
• Est. Priority Date: 11/13/1992
• Status: Expired due to Term

• Current Assignee: Mark Tierney, Richard Dimonda
• Original Assignee: Mark Tierney, Richard Dimonda
• Inventors: Tierney, Mark, diMonda, Richard
• Primary Examiner(s): Dvorak, Linda C. M.
• Assistant Examiner(s): ROLLINS, ROSILAND STACIE
• Application Number:
  US08/898,655
• Time in Patent Office: 1,358 Days
• Field of Search: 607/100-102, 607/104, 607/105, 607/113, 607/154, 607/156, 606/192, 128/898
• US Class Current: 607/101
• CPC Class Codes: A61B 18/18 by applying electromagnetic radiation, e.g. microwaves radiation therapy A61N5/00
• CPC Class Codes: A61B 18/1815 using microwaves
• CPC Class Codes: A61B 18/24 with a catheter A61B18/26, A61B18/28 take precedence
• CPC Class Codes: A61B 2017/00092 using thermocouples
• CPC Class Codes: A61B 2017/00106 ultrasonic
• CPC Class Codes: A61B 2017/00274 Prostate operation, e.g. prostatectomy, turp, bhp treatment
• CPC Class Codes: A61B 2017/22051 with an inflatable part, e.g. balloon, for positioning, blocking, or immobilisation A61B2017/22048, A61B2017/3486 take precedence
• CPC Class Codes: A61B 2017/22065 Functions of balloons dilating A61M29/02
• CPC Class Codes: A61B 2018/00017 with gas
• CPC Class Codes: A61B 2018/00547 Prostate
• CPC Class Codes: A61B 2090/0472 against ultrasound energy
• CPC Class Codes: A61B 2090/0481 against EM radiation, e.g. microwave
• CPC Class Codes: A61B 2090/049 against light, e.g. laser
• CPC Class Codes: A61B 2090/378 using ultrasound
• CPC Class Codes: A61B 2090/3925 ultrasonic
• CPC Class Codes: A61B 90/04 Protection of tissue around surgical sites against effects of non-mechanical surgery, e.g. laser surgery protection of eyes against laser radiation A61F9/022
• CPC Class Codes: A61F 2007/0095 with a temperature indicator
• CPC Class Codes: A61F 7/12 Devices for heating or cooling internal body cavities
• CPC Class Codes: A61N 5/04 Radiators for near-field treatment
• CPC Class Codes: A61N 5/045 specially adapted for treatment inside the body
• CPC Class Codes: A61N 7/02 : Localised ultrasound hyperthermia hyperthermia in general A61F7/00
• CPC Class Codes: A61N 7/022 : intracavitary

Abstract

A thermotherapy device for treatment of diseased biological tissues. The thermotherapy device includes a primary and at least one secondary cooling and/or radiation shielding lumen. The lumens are connected or disposed adjacent one another along their longitudinal exterior walls. An energy source is insertable into one or more of the cooling lumens to carry out a heating protocol to treat the diseased tissue while screening and/or cooling normal tissue. A transrectal ultrasound positioning and temperature sensing device can control the energy source for effective treatment.

Claims

1. A method for performing thermotherapy treatment of patient prostate tissue, comprising the steps of:

inserting a thermotherapy probe into a urethra, said probe having a fluid volume containing portion and an energy source disposed therein for generating radiation to heat the patient prostate tissue by the tissue absorbing the radiation;

generating a pressurized fluid flow in said probe within said fluid volume containing portion and cooling the energy source by enveloping at least a portion of the energy source to direct said pressurize fluid flow to come into direct contact with and circulate around and over energy radiation portions of the energy source simultaneously with energy radiation by the energy source, preventing thermal damage to the energy source and improving energy radiation transfer;

providing an inflatable substantially nondistensible structure as part of said probe inserted into the urethra, said inflatable substantially nondistensible structure including a first lumen having a generally circular cross-section in which said energy source is disposed, and a second lumen having a laterally elongated cross-section which is connected externally to and extends substantially parallel to the first lumen; and

straightening the urethra by inflating said substantially nondistensible structure with said pressurized fluid flow.

2. The method as defined in claim 1, further including the step of remotely indicating tissue temperatures during treatment by sensing the temperature of said fluid.

3. The method as defined in claim 2, further including the step of detecting a position of said probe.

4. The method as defined in claim 1, wherein said energy source is disposed along a centerline of said first lumen.

5. An apparatus for performing thermotherapy treatment of patient prostate tissue, comprising:

a thermotherapy probe adapted to be inserted into a urethra, and said probe having a fluid volume containing portion and an energy source disposed therein for generating radiation to heat the patient prostate tissue by the tissue absorbing the radiation,

the fluid volume containing portion including a cooling structure for containing a pressurized fluid flow for cooling the energy source, said cooling structure enveloping at least a portion of the energy source to direct said pressurized fluid flow to come into direct contact with and circulate around and over all energy radiation portions of the energy source simultaneously with energy radiation by the energy source, preventing thermal damage to the energy source and improving energy radiation transfer, and

said fluid volume containing portion further including an inflatable substantially nondistensible structure in fluid communication with said cooling structure and adapted to become substantially rigid so as to straighten the urethra when said probe is inserted into the urethra and said substantially nondistensible structure is inflated with said pressurized fluid flow, said inflatable nondistensible structure including a first lumen having a generally circular cross-section in which said energy source is disposed, and a second lumen having a laterally elongated cross-section which is connected externally to and extends substantially parallel to the first lumen.

6. A thermotherapy probe, comprising:

a first lumen having a generally circular cross-section;

an energy source disposed inside the first lumen; and

a second lumen having a generally oval cross-section which is connected externally to and extends substantially parallel to the first lumen;

the first and second lumens being configured to allow cooling fluid to flow therethrough.

7. A probe as defined in claim 6 in which the first and second lumens are configured such that fluid flows through the first lumen in a first direction, flows from the first lumen into the second lumen, and flows through the second lumen in a second direction which is opposite to the first direction.

8. A probe as defined in claim 6, in which the first and second lumens are configured such that fluid flows through the second lumen in a first direction, flows from the second lumen into the first lumen, and flows through the first lumen in a second direction which is opposite to the first direction.

9. A probe as defined in claim 6, further comprising a third lumen having a generally oval cross-section which is connected externally to and extends substantially parallel to the first lumen.

10. A probe as defined in claim 9, in which the second and third lumens are connected to opposites of the first lumen.

11. A method of performing thermotherapy, comprising the steps of:

placing a thermotherapy probe in proximity to an organ to be treated, the probe including a first lumen having a generally circular cross-section, an energy source disposed inside the first lumen, and a second lumen having a generally oval cross-section which is connected externally to and extends substantially parallel to the first lumen, the first and second lumens being configured to allow cooling fluid to flow therethrough;

energizing the energy source; and

causing cooling fluid to flow through the first and second lumens.

12. A method for performing thermotherapy treatment of patient prostate tissue, comprising:

inserting a thermotherapy probe into a urethra, said probe having a fluid volume containing portion made of an inflatable substantially nondistensible structure and an energy source disposed therein for generating radiation to heat the patient prostrate tissue by the tissue absorbing the radiation;

generating a pressurized fluid flow in said probe within said fluid volume containing portion and cooling the energy source by enveloping at least a portion of the energy source to direct said pressurize fluid flow to come into direct contact with and circulate around and over energy radiation portions of the energy source simultaneously with energy radiation by the energy source;

providing said probe in a non-straightened condition in said urethra;

straightening said urethra by inflating said substantially nondistensible structure so as to cause said substantially nondistensible structure to straighten.

13. An apparatus for performing thermotherapy treatment of patient prostate tissue, comprising:

a thermotherapy probe adapted to be inserted into a urethra, and said probe having a fluid volume containing portion made of an inflatable substantially nondistensible structure and an energy source disposed therein for generating radiation to heat patient prostrate tissue, the fluid volume containing portion adapted to receive a pressurized fluid flow that comes into direct contact with and circulates around and over energy radiation portions of the energy source simultaneously with energy radiation by the energy source, said substantially nondistensible structure adapted to go from a non-straight condition to a straight condition when said substantially nondistensible structure is inflated with said pressurized fluid flow so as to straighten the urethra when said probe is disposed in the urethra, enabling greater uniformity and effectiveness of treatment of the prostate tissue.

14. A thermotherapy probe, comprising:

a first lumen including an energy source disposed therein and an outer surface adapted to contact body tissue;

a secondary lumen connected externally to and extending substantially parallel to the first lumen and including an outer surface adapted to contact body tissue; and

the first and second lumens being configured to allow cooling fluid to flow therethrough and having an asymmetric structure that enables application of radiation to be preferentially directed to targeted tissue, giving rise to more effective treatment with thermothreapy, while also preventing tissue damage to non-targeted tissue.

15. A method of performing thermotherapy, comprising the steps of:

placing a thermotherapy probe in proximity to an organ to be treated, the probe including a first lumen having an energy source disposed therein and an outer surface adapted to contact body tissue, a secondary lumen connected externally to and extending substantially parallel to the first lumen and having an outer surface adapted to contact body tissue, the first and second lumens being configured to allow cooling fluid to flow therethrough and having an asymmetric structure that enables application of radiation to be preferentially directed to targeted tissue, giving rise to more effective treatment with thermothreapy, while also preventing tissue damage to non-targeted tissue;

physically shifting the first lumen and energy source disposed therein toward targeted tissue for radiation treatment and away from untargeted tissue upon placement of said asymmetric first and second lumens of said probe in proximity to the organ to be treated;

energizing the energy source; and

causing cooling fluid to flow through the first and second lumens.