×

Patterned binding of functionalized microspheres for optical diffraction-based biosensors

  • US 6,221,579 B1
  • Filed: 12/11/1998
  • Issued: 04/24/2001
  • Est. Priority Date: 12/11/1998
  • Status: Expired due to Term
First Claim
Patent Images

1. A method of detecting an analyte in a medium comprising:

  • adding a diffraction enhancing element to the medium suspected of containing the analyte, wherein the diffraction enhancing element has a receptor material thereon that is specific for the analyte;

    contacting the medium with a sensing device, the sensing device comprising;

    a polymer film; and

    an analyte-specific receptor layer printed in a pattern onto the polymer film wherein the analyte-specific receptor layer has a receptor material thereon that is specific for the analyte, and wherein the receptor layer is not a self-assembling monolayer;

    transmitting a light through the polymer film; and

    detecting presence of the analyte by detecting a pattern formed by diffraction of the transmitted light.

View all claims
  • 2 Assignments
Timeline View
Assignment View
    ×
    ×