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Semi-interpenetrating or interpenetrating polymer networks for drug delivery and tissue engineering

  • US 6,224,893 B1
  • Filed: 05/23/1997
  • Issued: 05/01/2001
  • Est. Priority Date: 04/11/1997
  • Status: Expired due to Term
First Claim
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1. A method for forming a tissue equivalent in a patient, comprising:

  • providing a suspension of dissociated cells in a solution of a biocompatible polymer, wherein the polymer crosslinks upon exposure to free radicals to form a hydrogel, injecting said suspension into a patient, and exposing the suspension in situ to free radicals generated by electromagnetic radiation from an electromagnetic source external to the injected suspension, the electromagnetic radiation penetrates through tissue to generate the free radicals which cause polymer crosslinking and whereby the tissue equivalent forms.

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