Magnetic resonance imaging method and system with adaptively selected flip angels

• US 6,230,039 B1
• Filed: 03/28/2000
• Issued: 05/08/2001
• Est. Priority Date: 03/28/2000
• Status: Expired due to Fees

• Current Assignee: Philips Electronics North America Corporation (Koninklijke Philips N.V.)
• Original Assignee: Philips Electronics North America Corporation (Koninklijke Philips N.V.)
• Inventors: Botnar, Rene, Stuber, Matthias
• Primary Examiner(s): Lateef, Marvin M.
• Assistant Examiner(s): MANTIS MERCADER, ELENI M
• Application Number:
  US09/536,943
• Time in Patent Office: 406 Days
• Field of Search: 600/410, 600/413, 600/419, 324/307, 324/309, 324/306
• US Class Current: 600/410
• CPC Class Codes: A61B 5/055 involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
• CPC Class Codes: G01R 33/5676 Gating or triggering based on an MR signal, e.g. involving one or more navigator echoes for motion monitoring and correction

Abstract

This invention relates to methods and apparatus for magnetic resonance (MR) imaging of moving parts of a patient in which flip angles for the excitation of nuclear magnetization are adaptively selected during image data acquisition in order to minimize artifacts. In particular, the flip angles are selected so that a smooth distribution of signal-strengths in k-space results even though the order of phase-encoding gradients is also adaptively selected in dependence of the measured instantaneous state of motion of the moving part. The invention also includes MR apparatus for practicing the described methods and software for controlling an MR apparatus to practice the methods.

Claims

1. A magnetic resonance (MR) method for imaging a moving object with reduced motion artifacts, the method comprising:

measuring the instantaneous state of motion of the object present in an examination zone,

selecting phase-encoding gradients wherein the time integrals of the selected phase-encoding gradients depend at least in part on the measured instantaneous state of motion,

selecting flip angles, wherein the selected flip angles depend at least in part on the previously selected phase-encoding gradients or on the measured instantaneous state of motion,

generating MR signals from the object by applying RF pulses to excite nuclear magnetization with the selected flip angles and by applying the selected phase-encoding gradients, and

reconstructing an MR image from the generated MR signals.

2. The method of claim 1 wherein the object moves in a repetitive manner.

3. The method of claim 1 wherein the selected phase-encoding gradients depend on previously selected phase-encoding gradients, and wherein a phase encoding gradient is selected only if that phase-encoding gradient has not previously been selected.

4. The method of claim 1 wherein the instantaneous state of motion of the object is represented by a measured instantaneous displacement in a pre-determined direction, and wherein the selected phase-encoding gradients are in the pre-determined direction.

5. The method of claim 4 wherein the step of measuring comprises generating and receiving MR navigator signals.

6. The method of claim 4 wherein a phase-encoding gradient is selected only if the measured displacement does not exceed a threshold value of the displacement, wherein the threshold value of the displacement depends in an increasing manner on the time integral of the phase-encoding gradient.

7. The method of claim 1 wherein the instantaneous state of motion of the object is represented by instantaneously measured displacements in two pre-determined directions, and wherein the phase-encoding gradients are in the two predetermined directions.

8. The method of claim 1 wherein the selected flip angles depend on the previously selected time integrals of the phase-encoding gradients so that the signal strength of the excited MR signal varies smoothly in k-space according to an arbitrary function.

9. The method of claim 8 wherein the smooth variation in k-space is a constant signal strength.

10. The method of claim 8 wherein the smooth variation in k-space is represented by a circularly symmetric function that is monotonically decreasing from the center to the periphery of k-space.

11. The method of claim 10 wherein the smooth variation in k-space is a Gaussian having a maximum at the center of k-space.

12. The method of claim 1 wherein the selected flip angles depend also on the previously measured instantaneous state of motion.

13. The method of claim 1 further comprising determining the expected state of nuclear magnetization prior to application of the next RF pulse, and wherein the selected flip angles depend also at least in part on the determined expected state of nuclear magnetization.

14. The method of claim 13 wherein a plurality of MR signal generating steps are grouped together into a shot.

15. The method of claim 13 wherein determining the expected state of nuclear magnetization comprises determining the expected state of longitudinal nuclear magnetization neglecting residual transverse nuclear magnetization.

16. The method of claim 13 wherein determining the expected state of nuclear magnetization comprises determining the expected state of longitudinal nuclear magnetization considering residual transverse nuclear magnetization.

17. The method of claim 1 wherein MR signals are generating with a repeat time which is much less than the relaxation time of longitudinal nuclear magnetization.

19. A computer readable media carrying encoded program instructions for causing a programmable MR apparatus to perform the method of claim 1.

18. A magnetic resonance (MR) apparatus for acquiring images of a moving part of a patient placed in an examination zone of the MR apparatus with reduced motion artifacts, the apparatus comprising:

a main magnet system for generating a steady magnetic field in the examination zone,

a gradient magnet system for generating temporary gradient magnetic fields in the examination zone,

a radio frequency (RF) transmitter system for generating RF pulses in the examination zone,

an RF receiver system for receiving MR signals from the examination zone,

a reconstruction unit for reconstructing an image of the region of the patient from the received MR signals,

a control unit for generating signals controlling the gradient magnet system, the RF transmitter system, the RF receiver system, and the reconstruction unit, wherein the control unit generates signals causing

measurement of the instantaneous state of motion of the object present in an examination zone,

selecting of phase-encoding gradients wherein the time integrals of the selected phase-encoding gradients depend at least in part on the measured instantaneous state of motion,

selecting of flip angles, wherein the selected flip angles depend at least in part on the previously selected phase-encoding gradients or on the measured instantaneous state of motion,

generating of MR signals from the object by applying RF pulses to excite nuclear magnetization with the selected flip angles and by applying the selected phase-encoding gradients, and

reconstructing of an MR image from the generated MR signals.