Method of localized fluid therapy

• US 6,231,591 B1
• Filed: 06/26/1998
• Issued: 05/15/2001
• Est. Priority Date: 10/18/1991
• Status: Expired due to Fees

• Current Assignee: 2000 Injectx, Inc.
• Original Assignee: 2000 Injectx, Inc.
• Inventors: Desai, Ashvin H.
• Primary Examiner(s): Brown, Michael A.
• Application Number:
  US09/105,896
• Time in Patent Office: 1,054 Days
• Field of Search: 606/210, 606/211, 604/8, 604/9, 604/10
• US Class Current: 606/210
• CPC Class Codes: A61B 1/018 for receiving instruments
• CPC Class Codes: A61B 17/00234 for minimally invasive surgery A61B17/0218, A61B17/0469, A61B17/12013, A61B17/1285, A61B17/29, A61B17/320016 take precedence
• CPC Class Codes: A61B 17/3403 Needle locating or guiding means guides for suture needles A61B17/0482; guiding or tracking by nuclear magnetic resonance G01R33/285
• CPC Class Codes: A61B 17/3498 Valves therefor, e.g. flapper valves, slide valves haemostasis valves A61M39/06; check valves A61M39/24
• CPC Class Codes: A61B 18/14 Probes or electrodes therefor
• CPC Class Codes: A61B 18/1402 Probes for open surgery
• CPC Class Codes: A61B 18/1442 Probes having pivoting end effectors, e.g. forceps
• CPC Class Codes: A61B 18/1477 Needle-like probes
• CPC Class Codes: A61B 18/1482 having a long rigid shaft for accessing the inner body transcutaneously in minimal invasive surgery, e.g. laparoscopy
• CPC Class Codes: A61B 18/149 bow shaped or with rotatable body at cantilever end, e.g. for resectoscopes, or coagulating rollers
• CPC Class Codes: A61B 2017/00026 Conductivity or impedance, e.g. of tissue
• CPC Class Codes: A61B 2017/00274 Prostate operation, e.g. prostatectomy, turp, bhp treatment
• CPC Class Codes: A61B 2017/00464 for use with different instruments with hole for different instruments A61B2017/22072
• CPC Class Codes: A61B 2017/22072 with an instrument channel, e.g. for replacing one instrument by the other in cannulas A61B17/3417
• CPC Class Codes: A61B 2017/3411 with a plurality of holes, e.g. holes in matrix arrangement
• CPC Class Codes: A61B 2018/00547 Prostate
• CPC Class Codes: A61B 2018/0091 Handpieces of the surgical instrument or device
• CPC Class Codes: A61B 2018/00916 with means for switching or controlling the main function of the instrument or device
• CPC Class Codes: A61B 2018/00982 combined with or comprising means for visual or photographic inspections inside the body, e.g. endoscopes
• CPC Class Codes: A61B 2018/1253 monopolar
• CPC Class Codes: A61B 2018/126 : bipolar
• CPC Class Codes: A61B 2018/1425 : Needle
• CPC Class Codes: A61B 2218/002 : Irrigation
• CPC Class Codes: A61B 2218/007 : Aspiration
• CPC Class Codes: A61B 6/12 : Arrangements for detecting or locating foreign bodies
• CPC Class Codes: A61B 8/0841 : for locating instruments
• CPC Class Codes: A61M 1/772 : operating alternately
• CPC Class Codes: A61M 1/774 : Handpieces specially adapted for providing suction as well as irrigation, either simultaneously or independently
• CPC Class Codes: A61N 5/0601 : Apparatus for use inside the body
• CPC Class Codes: A61N 5/062 : Photodynamic therapy, i.e. excitation of an agent

Abstract

A method and apparatus for treating a localized portion of body tissue including an endoscopic surgical instrument including a probe with a canal for guiding a hollow core needle assembly, the assembly having apparatus for extending and retracting a needle relative to the probe. According to the method, the needle is extended into body tissue to deliver a treatment fluid to a localized portion.

Claims

1. A method for treating a localized portion of body tissue comprising:

(a) inserting a means for delivering fluid into said body;

(b) positioning said means for delivering fluid at a target tissue in need of treatment; and

(c) applying fluid to said target tissue through said means for delivering fluid.

2. A method as recited in claim 1 wherein said applying includes depositing fluid on a surface of said tissue.

3. A method as recited in claim 1 wherein said applying includes penetrating said tissue to a desired depth with said means for delivering fluid.

4. A method as recited in claim 1 wherein said inserting includes inserting said means for delivering fluid through a natural opening in said body.

5. A method as recited in claim 1 wherein said inserting includes inserting said means for delivering fluid through an incision in said body.

6. A method as recited in claim 1 wherein said applying is restricted to a desired localized portion of tissue so as not to effect surrounding tissue.

7. A method as recited in claim 1 wherein said needle means includes a single hollow core needle.

8. A method as recited in claim 1 wherein said needle means includes a plurality of hollow core needles.

9. A method as recited in claim 1 wherein said fluid is a mixture of fluids.

10. A method as recited in claim 1 wherein said fluid includes a tissue necrossing agent.

11. A method as recited in claim 10 wherein said fluid further includes an anesthetic agent.

12. A method as recited in claim 10 wherein said fluid further includes an antibiotic.

13. A method as recited in claim 1 wherein said fluid is a mixture of a plurality of different fluids.

14. A method as recited in claim 1 wherein said fluid is a gel.

15. A method a recited in claim 1 wherein said fluid is a semi-liquid.

20. A method as recited in claim 1 wherein said adjusting includes guiding said needle apparatus with a guiding apparatus.

21. A method as recited in claim 20 wherein said guiding apparatus is an endoscope.

22. A method as recited in claim 20 wherein said guiding apparatus includes non-invasive detection positioning and imaging apparatus.

23. A method as recited in claim 1 wherein said inserting includes inserting said needle apparatus by puncturing said tissue.

16. An apparatus for treating a targeted body tissue comprising;

(a) a hollow core needle means; and

(b) a probe for entering into said body, said probe having a canal means through which said needle means can be inserted, said needle means for applying fluid to said tissue.

17. An apparatus as recited in claim 16 wherein said needle means includes a hole in a sidewall for delivery of said fluid.

18. A method as recited in claim 16 wherein said needle apparatus includes a needle tip means at a distal end, needle apparatus having a treatment fluid delivery hole, and said needle apparatus having a fluid block for preventing fluid ejected from said fluid delivery hole from flowing between an outside of said needle apparatus and said tissue toward a proximal end of said needle apparatus.

19. A method as recited in claim 18 wherein said needle apparatus further includes a plurality of holes spaced along a length of said needle for delivery of said treatment fluid, and wherein said needle apparatus further includes a sleeve installed over said needle for selectively exposing a first plurality of said holes for controlling an area of tissue to be treated.

24. An apparatus for treating a targeted body tissue comprising:

(a) a needle apparatus including a hollow core needle for delivery of a treatment fluid to said targeted body tissue for treatment of said tissue;

(b) a probe for entering into said body, said probe having a canal through which said needle apparatus can be inserted; and

(c) adjustment apparatus for extending a distal end of said hollow core needle to a position beyond a distal end of said probe to said targeted tissue for deposition of said treatment fluid.

25. An apparatus as recited in claim 24 wherein said needle apparatus includes a hole in a sidewall for delivery of said treatment fluid.

26. An apparatus as recited in claim 24 wherein said needle apparatus includes a plurality of needles.

27. An apparatus as recited in claim 24 wherein said needle apparatus includes one or more needles constructed of resilient material pre-stressed in a curved shape.

28. An apparatus for treating a targeted body tissue comprising:

needle apparatus including a hollow core needle for penetrating a targeted body tissue, said hollow core needle having a treatment fluid delivery hole, and said needle apparatus having a fluid block for preventing fluid ejected from said fluid delivery hole near the distal end of said hollow core needle from flowing between the outside of said needle apparatus and said tissue toward the proximal end of said needle apparatus, wherein said needle apparatus further includes a plurality of holes spaced along a length of said hollow core needle for delivery of said treatment fluid, and wherein said fluid block includes a sleeve installed over said hollow core needle for selectively exposing a first quantity of said holes for controlling an area of tissue to be treated.