Storage and transport system for sample material

• US 6,231,815 B1
• Filed: 11/20/1997
• Issued: 05/15/2001
• Est. Priority Date: 12/03/1996
• Status: Expired due to Term

• Current Assignee: Roche Diagnostics GmbH (Roche Holding AG)
• Original Assignee: Roche Diagnostics GmbH (Roche Holding AG)
• Inventors: Leininger, Helmut, Lerch, Rolf, Bainczyk, Gregor, Nagel, Rolf
• Primary Examiner(s): ALEXANDER, LYLE
• Application Number:
  US08/974,481
• Time in Patent Office: 1,272 Days
• Field of Search: 435/307.1, 435/304.1, 206/204, 422/58, 422/61, 422/99, 422/100, 422/102, 422/104, 738/647.1, 738/647.2
• US Class Current: 422/550
• CPC Class Codes: B01L 2200/18 Transport of container or devices
• CPC Class Codes: B01L 2300/042 Caps; Plugs
• CPC Class Codes: B01L 2300/0825 Test strips
• CPC Class Codes: B01L 2300/0887 Laminated structure
• CPC Class Codes: B01L 2300/105 using desiccants
• CPC Class Codes: B01L 2400/0406 capillary forces
• CPC Class Codes: B01L 3/5023 with a sample being transported to, and subsequently stored in an absorbent for analysis

Abstract

The invention concerns a system for the storage and transport of sample material on absorbent material which is characterized in that the system contains no test reagents and it additionally includes a closable container containing a medium that can absorb moisture such as a desiccant in addition to the absorbent material for absorbing a liquid sample. Furthermore the system according to the invention can contain an agent to stabilize the sample material and optionally further auxiliary substances.

Claims

1. A system for storage and transport of sample material on absorbent material comprising a closable container containing a medium that absorbs moisture and a first layer and a second layer of absorbent material for absorbing a liquid sample attached to an inert support, said first layer and said second layer of absorbent material arranged next to and touching another on said inert support and contacted to enable transfer of liquid such that liquid can pass from said first layer into said second layer when said first layer is filled with liquid and said first layer can be completely separated from said second layer after a sample material has been applied and dried, said absorbent material for said first and said second layers being selected from the group consisting of papers, filter papers, fleeces, fabrics, knitted fabrics and membranes, and does not contain test reagents.

2. The system of claim 1, wherein said absorbent material further comprises auxiliary substances to spread the liquid sample.

3. The system of claim 1, wherein said absorbent material further comprises a marking on the sample application zone.

4. The system of claim 1, wherein said system is provided with handling instructions.

5. The system of claim 1, wherein said medium that absorbs moisture comprises a dessicant.

6. The system of claim 5, wherein said desiccant is selected from the group consisting of silica gels, zeolites, clays and combinations thereof.

7. The system of claim 1, wherein said closable container comprises a tube that can be closed with a member selected from the group consisting of a stopper and a cap.

8. The system of claim 7, wherein said stopper or cap comprises a non-deformable, unbreakable material that is inert towards the sample.

9. The system of claim 8, wherein said tube is made of a member selected from the group consisting of a plastic, a metal, alloys, paper, cardboard, ceramics, and glass.

10. The system of claim 9, wherein said tube is made of a material selected from the group consisting of polyethylene, polypropylene and aluminum.

11. The system of claim 1, wherein said medium which absorbs moisture is permanently attached to said closable container or to a part thereof.

12. The system of claim 1, wherein said closable container comprises a member selected from the group consisting of an envelope having a foldable edge and a bag having a foldable edge.

13. The system of claim 1, wherein said absorbent material further comprises stabilizers for the sample.

14. The system of claim 13, wherein said absorbent material comprises a boric acid buffer with a pH larger than or equal to 10.5.

15. The system of claim 7, wherein said tube comprises a non-deformable unbreakable material that is inert towards the sample.

16. The system of claim 9, wherein said paper is coated with a member selected from the group consisting of plastic, metal, and alloys.

17. The system of claim 9, wherein said cardboard is coated with a member selected from the group consisting of plastic, metal, and alloys.

18. The system of claim 13, wherein said absorbent material further comprises a transition metal salt.