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Bioadhesive microspheres and their use as drug delivery and imaging systems

  • US 6,235,313 B1
  • Filed: 03/26/1997
  • Issued: 05/22/2001
  • Est. Priority Date: 04/24/1992
  • Status: Expired due to Fees
First Claim
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1. A drug formulation comprising drug encapsulated within a microsphere having a diameter between about 1 μ

  • m and 5 mm and a synthetic polymeric surface with a composition and morphology providing a sufficient concentration of carboxylic acid end groups at the surface, such that the surface adhesive force is equivalent to an adhesive force of between 110 N/m2 and 100,000 N/m2 measured on rat intestine.

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  • 6 Assignments
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