Dispensing system

• US 6,237,589 B1
• Filed: 03/22/1999
• Issued: 05/29/2001
• Est. Priority Date: 06/20/1996
• Status: Expired due to Term

• Current Assignee: Profile Respiratory Systems Limited
• Original Assignee: Medic-Aid Limited
• Inventors: Denyer, Jonathan Stanley Harold, Basista, Jacek Lech, Dyche, Anthony
• Primary Examiner(s): Lewis, Aaron J.
• Assistant Examiner(s): SRIVASTAVA, VIRENDRA KUMAR
• Application Number:
  US09/202,748
• Time in Patent Office: 799 Days
• Field of Search: 128/200.21, 128/200.18, 128/200.22, 128/200.14, 128/200.16, 128/203.23, 128/203.24, 128/204.26, 128/204.23
• US Class Current: 128/200.21
• CPC Class Codes: A61M 11/06 of the injector type
• CPC Class Codes: A61M 2016/0021 with a proportional output signal, e.g. from a thermistor
• CPC Class Codes: A61M 2016/0027 pressure meter
• CPC Class Codes: B05B 7/0012 Apparatus for achieving spraying before discharge from the apparatus

Abstract

A product dispensing system comprises a calibrated nebulizer having a nebulizer jet, mouthpiece, means for sourcing compressed air, a manifold for distributing the source of compressed air in at least one direction, a nebulizer accommodation means which is accessed by port, and a valve means for controlling the manifold and thereby the flow of compressed air to the port. The manifold and the port are linked by a length of tube, wherein the internal volume of the tube from the manifold outlet to the nebulizer jet is less than 0.7 ml.

Claims

1. A product dispensing system comprising:

a calibrated nebulizer having a nebulizer jet;

a mouthpiece;

means for sourcing compressed air;

a manifold for distributing the compressed air in at least one direction;

a port;

a nebulizer accommodation means which is accessed by the port;

a valve means for controlling the manifold and thereby the flow of compressed air to the port; and

a length of tube linking the manifold and the port, the internal volume of which, from the manifold outlet to the nebulizer jet, is less than 0.7 ml.

2. A dispensing system as claimed in claim 1, wherein the manifold is integral with the valve means.

3. A dispensing system as claimed in claim 1, additionally comprising a compressor having a flow rate of 1-2 liters per minute and an accumulator.

4. A dispensing system as claimed in claim 1, additionally comprising a switch means which is responsive as to whether compressed air is flowing in the system.

5. A dispensing system as claimed in claim 1, further comprising a dosimeter which has been pre-programmed to dose one or more medicaments according to predetermined dosage profiles.

6. A dispensing system according to claim 1, further comprising a pressure sensor which is capable, in use, of detecting a pressure drop in the apparatus in response to the patient'"'"'s breathing, whereby a pulse of nebulized medicament may be delivered into the mouthpiece.

7. A dispensing system according to claim 6 further comprising means for calculating the dosage of medicament on the basis of the known rate of medicament output against time for the selected drug.

8. A dispensing system according to claim 1, wherein the manifold is an integral part of the valve means.

9. A dispensing system according to claim 1, where the manifold is a shaped block with integral galleys the presence of which allows the tubes to be connected to the ports on the valve.

10. A dispensing system according to claim 1, further comprising a lightweight compressor system and an accumulator.

11. A dispensing system according to claim 10, wherein the lightweight compressor generates a low flow rate of the order of 1 to 2 liters per minute.

12. A dispensing system according to claim 10 wherein the combination of the low flow rate compressor and the accumulator allows the dispensing system to produce pulses of compressed air to the nebulizer with a flow of around of 6 litres per minute.

13. A dispensing system according to claim 12 wherein the combination of the low flow rate compressor and the accumulator allows the dispensing system to produce pulses of compressed air to the nebulizer with a flow of around of 6 litres per minute.

14. A dispensing system according to claim 11, wherein the valve means serves to switch the compressed air on and off.

15. A dispensing system according to claim 1, wherein the manifold together with the valve means serve to direct the flow of compressed air either to the nebulizer or to an outlet orifice.

16. A dispensing system according to claim 1, wherein the volume of the tube linking the manifold outlet to the nebulizer jet is less than 0.5 ml.

17. A dispensing system according to claim 1, wherein the nebulizer serves to deliver inspiratory pulses between 0.1 and 1.5 second in duration.

18. A dispensing system according to claim 10, wherein the accumulator includes an resilient elastic body having a generally linear pressure to volume relationship.

19. A dispensing system according to claim 18, wherein the resilient body is a generally hemispherical resilient element.

20. A dispensing system according to claim 19 wherein the hemispherical element is a diaphragm extendable to 500% of its unloaded volume.

21. A product dispensing system comprising:

a calibrated nebulizer having a nebulizer jet;

a mouthpiece;

means for sourcing compressed air;

a manifold for distributing the compressed air in at least one direction;

a port;

a nebulizer accommodation means which is accessed by the port;

a valve means for controlling the manifold and thereby the flow of compressed air to the port;

a length of tube linking the manifold and the port;

a compressor; and

an accumulator;

wherein the accumulator includes a resilient elastic body having a generally linear pressure to volume relationship.

22. A product dispensing system according to claim 21 wherein the internal volume of the tube from the manifold outlet to the nebulizer jet is less than 0.7 ml.

23. A product dispensing system comprising:

a calibrated nebulizer having a nebulizer jet;

a mouthpiece;

means for sourcing compressed air;

a manifold of distributing the compressed air in at least one direction;

a port;

a nebulizer accommodation means which is accessed by the port;

a valve means for controlling the manifold and thereby the flow of compressed air to the port;

a length of tube linking the manifold and the port;

a pressure sensor for detecting a drop in pressure in the apparatus in response to a patient'"'"'s breathing to indicate the rate of inhalation of the patient; and

means for determining the dose dispensed, the dose being determined on the basis of the output rate of the medicament of the nebulizer, and the duration of the delivery of the medicament, the dose determining means serving to adjust the value of the output rate on the basis of the rate of inhalation of the patient detected by the pressure sensor.

24. A system according to claim 23, wherein the internal volume of the tube from the manifold outlet to the nebulizer jet is less than 0.7 ml.