High frequency thermal ablation of cancerous tumors and functional targets with image data assistance

• US 6,241,725 B1
• Filed: 06/11/1996
• Issued: 06/05/2001
• Est. Priority Date: 12/15/1993
• Status: Expired due to Fees

• Current Assignee: Covidien AG (Medtronic Plc)
• Original Assignee: Sherwood Services AG
• Inventors: Cosman, Eric R.
• Primary Examiner(s): COHEN, LEE S
• Application Number:
  US08/661,802
• Time in Patent Office: 1,820 Days
• Field of Search: 606/41, 606/43, 606/49, 607/99, 607/101, 607/102, 607/113, 128/653.2, 128/660.03, 600/439, 600/411
• US Class Current: 606/41
• CPC Class Codes: A61B 18/1477 Needle-like probes
• CPC Class Codes: A61B 2018/00797 measured by multiple temperature sensors
• CPC Class Codes: A61B 2018/1425 Needle
• CPC Class Codes: A61B 2018/1467 using more than two electrodes on a single probe
• CPC Class Codes: A61B 2018/1475 Electrodes retractable in or deployable from a housing

Abstract

This invention relates to the destruction of pathological volumes or target structures such as cancerous tumors or aberrant functional target tissue volumes by direct thermal destruction. In the case of a tumor, the destruction is implemented in one embodiment of the invention by percutaneous insertion of one or more radiofrequency probes into the tumor and raising the temperature of the tumor volume by connection of these probes to a radiofrequency generator outside of the body so that the isotherm of tissue destruction enshrouds the tumor. The ablation isotherm may be predetermined and graded by proper choice of electrode geometry and radiofrequency (rf) power applied to the electrode with or without temperature monitoring of the ablation process. Preplanning of the rf electrode insertion can be done by imaging of the tumor by various imaging modalities and selecting the appropriate electrode tip size and temperature to satisfactorily destroy the tumor volume. Computation of the correct three-dimensional position of the electrode may be done as part of the method, and the planning and control of the process may be done using graphic displays of the imaging data and the rf ablation parameters. Specific electrode geometries with adjustable tip lengths are included in the invention to optimize the electrodes to the predetermined image tumor size.

Claims

1. A radio frequency heating process for the ablation of target tissue in the body of a patient, comprising the steps of:

storing image scanner data taken by volumetric image data acquisition from the body of the patient including the target tissue;

using said stored image scanner data to display a real time image of the body of the patient including the target tissue;

providing an elongated electrode structure with an insulating cover to define an exposed tip extending from said cover;

based on the displayed image of the body of the patient including the target tissue, inserting said elongated electrode structure into the body of the patient to position said tip contiguous to the target tissue; and

based on the displayed image of the body of the patient including the target tissue, energizing said elongated electrode structure with radio frequency electrical energy to radiate energy from said tip for ablating the target tissue in the body of the patient.

2. A process in accordance with claim 1 wherein the step of providing an elongated electrode structure further includes the provision of at least one electrode with said exposed tip of at least 12 millimeters length and at least 2.5 millimeters diameter.

3. A process in accordance with claim 1 wherein the step of providing an elongated electrode structure includes providing a plurality of shafts defining a plurality of tips to be positioned contiguous to the target tissue.

4. A process in accordance with claim 1 wherein the step of providing an elongated electrode structure includes providing an electrode with a variable length exposed tip extending from said cover.

5. A process in accordance with claim 1 wherein said step of displaying an image comprises displaying a real time image of the body of the patient including the target tissue using the image scanner data to drive a computer graphics workstation.

6. A process in accordance with claim 5 wherein said step of displaying further includes displaying functions of ablating said target tissue in the body of the patient.

7. A process in accordance with claim 1 wherein said step of storing image scanner data comprises storing data from a CT, MRI, ultrasonic or SPEC scanning means.

8. A process in accordance with claim 1 further including a step of utilizing an ultrasonic monitor to monitor the ablating of the target tissue.

9. A process according to claim 1 further including a step of affixing a stereotactic arc system to the patient and affixing said elongated electrode structure to be held stereotactically by said stereotactic arc system.

10. A process according to claim 1 further including a step of monitoring critical lesion parameters attendant the ablation of the target tissue and displaying said critical lesion parameters with said displayed image of the body of the patient including the target tissue.

11. A process according to claim 1 wherein the step of providing an elongated electrode structure is partly based on the displayed image of the body of the patient including the volume of the target tissue.