Multichannel pipette system and pipette tips therefor
First Claim
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1. A multichannel pipetting system comprising:
- a multichannel pipettor comprising a plurality of channels arranged in a two dimensional array, each channel having an aspirating and dispensing end, and means for simultaneous aspirating and dispensing in all channels;
a head comprising a channel support plate placed at said aspirating and dispensing end of the channels, said channel support plate having a plurality of holes corresponding to said plurality of channels and arranged in the same array as said plurality of channels such that the end of each channel is flush with the channel support plate and aligned with a hole of said channel support plate;
a plurality of pipette tips, each tip having a crown and a dispensing tip at opposite ends, said crown having a shape sufficient to be sealed over more than one hole of said channel plate, and a means for creating an air tight seal between said pipette tips and said channel support plate.
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Abstract
The present invention relates generally to a multichannel pipetting system that can be used with a plurality of well plates used for medical, biological or biochemical research involving liquid materials. The system includes a multichannel pipettor and novel pipette tips having a crown that can be fitted over the opening of more than one channel. The multichannel pipettor may optionally be provided with an array of air pressure channels placed among the array of pipetting channels and enables the pipettor to aspirate and dispense a crude large volume of liquid material through the novel pipette tips of the present invention.
67 Citations
13 Claims
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1. A multichannel pipetting system comprising:
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a multichannel pipettor comprising a plurality of channels arranged in a two dimensional array, each channel having an aspirating and dispensing end, and means for simultaneous aspirating and dispensing in all channels;
a head comprising a channel support plate placed at said aspirating and dispensing end of the channels, said channel support plate having a plurality of holes corresponding to said plurality of channels and arranged in the same array as said plurality of channels such that the end of each channel is flush with the channel support plate and aligned with a hole of said channel support plate;
a plurality of pipette tips, each tip having a crown and a dispensing tip at opposite ends, said crown having a shape sufficient to be sealed over more than one hole of said channel plate, and a means for creating an air tight seal between said pipette tips and said channel support plate. - View Dependent Claims (2, 3, 4, 11, 12)
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5. A pipette tip for use with a multichannel pipettor comprising:
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a proximal crown end to be sealed against said multichannel pipettor;
a distal dispensing tip end through which liquid material is to be aspirated and dispensed;
wherein said proximal crown end has a geometry such that the pipette tip can be fitted over more than one channel of said multichannel pipettor. - View Dependent Claims (6, 7)
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8. An arrangement of pipette tips for use with a multichannel pipettor and comprising a support plate and, supported therein, an array of a plurality of pipette tips, wherein each pipette tip comprises a proximal crown end to be sealed against said multichannel pipettor and a distal dispensing tip end through which liquid material is to be aspirated and dispensed;
wherein said proximal crown end has a geometry such that the pipette tip can be fitted over more than one channel of said multichannel pipettor. - View Dependent Claims (9, 10, 13)
Specification