Container for irradiation of blood products

• US 6,245,570 B1
• Filed: 09/15/1993
• Issued: 06/12/2001
• Est. Priority Date: 05/08/1991
• Status: Expired due to Fees

• Current Assignee: Baxter International Inc.
• Original Assignee: Baxter International Inc.
• Inventors: Leuenberger, Mark S., Grimm, Daniel J.
• Primary Examiner(s): LUDLOW, JAN M
• Application Number:
  US08/121,820
• Time in Patent Office: 2,827 Days
• Field of Search: 422/24, 422/102, 250/453.1, 250/454.1, 250/455.1, 250/492.1, 250/453.11, 250/455.11, 436/55, 604/6.08
• US Class Current: 436/55
• CPC Class Codes: A61J 1/10 Bag-type containers
• CPC Class Codes: A61J 1/1406 Septums, pierceable membranes
• CPC Class Codes: A61J 1/1462 Containers with provisions for hanging, e.g. integral adaptations of the container accessories for hanging the container A61M5/1414
• CPC Class Codes: A61J 1/1468 Containers characterised by specific material properties
• CPC Class Codes: A61J 1/1487 with friction fit, e.g. connecting tubes directly to a protruding port
• CPC Class Codes: A61J 2205/10 Bar codes
• CPC Class Codes: A61J 2205/20 Colour codes
• CPC Class Codes: A61J 2205/30 Printed labels
• CPC Class Codes: A61L 2/0011 using physical methods
• CPC Class Codes: A61L 2/10 Ultraviolet radiation
• CPC Class Codes: Y10T 436/12 Condition responsive control

Abstract

A container for irradiation comprises a flexible, flat collapsible wall defining a sealed chamber, the plastic material of said wall being substantially transparent to the irradiation, which is typically ultraviolet radiation. An access port or ports are provided for communicating through the wall to the chamber. A flap is provided, integral with the wall and spaced from the chamber. The flap carries identifying indicia including a typically bar code indicia, so that the wall which defines the chamber may be at least substantially free of opaque indicia. Also, means may be provided for detecting an indicating exposure of the container to such irradiation, such as ultraviolet sensitive tape adhering to the flap. Alignment holes may be provided, typically in the flap, to facilitate the orientation of the container with apparatus for irradiation and apparatus for bar code reading, making use of alignment pins carried by such apparatus. The irradiating apparatus may be of hinged section type, which carries a manually removable tray to define a support surface for a flexible container within the apparatus. The support surface is made of an ultraviolet-transmissive material such as quartz.

Claims

1. A method of irradiating a blood product which comprises placing a flexible, flat, collapsible bag having walls into a housing which defines a chamber, said bag holding a blood product containing white blood cells, the walls of said bag being made of a plastic material that is substantially transparent to ultraviolet irradiation;

said bag carrying a bar code relating to the contents of said bag;

securing said bag in the chamber by passing at least one pin positioned in said chamber through at least one preformed aperture of said bag, said aperture being spaced from the blood product therein, to automatically position said bag so that the bar code carried by the bag is in a position to be read by a bar code reader carried with the chamber;

automatically reading, via the bar code reader, the bar code of said bag within said chamber;

via software (a) automatically confirming by said bar code if the bag is approved for irradiation, (b) automatically irradiating the bag with ultraviolet radiation if the bag is approved but (c) automatically terminating the process without ultraviolet radiation if the bag carries a bar code indicating that the bag is not approved.

2. The method of claim 1 including the step of placing said bag in a tray having an ultraviolet permeable bottom wall, placing said tray in the chamber, and including the step of irradiating said bag through the ultraviolet permeable wall of said tray.

3. The method of claim 1 in which at least a pair of pins positioned in said chamber are passed through at least a pair of preformed apertures of said bag, said apertures being spaced from the blood product therein.

4. The method of claim 3 including the step of placing said bag in a tray having an ultraviolet permeable bottom wall, placing said tray in the chamber, and including the step of irradiating said bag through the ultraviolet permeable wall of said tray.

5. The method of claim 4 in which said bar code of the bag is carried on a flap of said bag which is spaced from the blood product carried therein, said at least one preformed aperture being also defined in said flap.

6. The method of claim 5 which includes the step of, prior to irradiating said bag, removing a protective tab from an ultraviolet radiation indicating patch carried on said bag.

7. The method of claim 6 in which a portion of said bag walls are in contact with said blood product, said portion being at least substantially free of opaque indicia.

8. The method of claim 6 in which a portion of said bag walls are in contact with said blood product, said portion being at least substantially free of opaque indicia.

9. A method of irradiating a blood product which comprises placing a flexible, flat, collapsible bag having walls into a housing which defines a chamber, said bag holding a blood product containing white blood cells, the walls of said bag being made of a plastic material that is substantially transparent to ultraviolet irradiation;

said bag carrying a bar code relating to the contents of said bag;

positioning the bag so that the bar code carried by the bag is in a position to be read by a bar code reader carried with the chamber;

automatically reading, via the bar code reader, the bar code of said bag within said chamber;

via software (a) automatically confirming by said bar code if the bag is approved for irradiation, (b) automatically irradiating the bag with ultraviolet radiation if the bag is approved, but (c) automatically terminating the process without ultraviolet radiation if the bag carries a bar code indicating that the bag is not approved.

10. The method of claim 9 including the step of placing said bag in a tray having an ultraviolet permeable bottom wall, placing said tray in the chamber, and including the step of irradiating said bag through the ultraviolet permeable wall of said tray.

11. The method of claim 9 in which said bar code of the bag is carried on a flap of said bag which is spaced from the blood product carried therein, said flap also defining at least a pair of preformed apertures for receiving a pair of said pins positioned in said chamber to automatically position said bag so that the bar code carried by the bag is in a position to be read by the bar code reader.

12. The method of claim 9 which includes the step, prior to irradiating said bag, of removing a protective tab from an ultraviolet radiation indicating patch carried on said bag.

13. The method of claim 9 in which a portion of said bag walls are in contact with said blood product, said portion being at least substantially free of opaque indicia.

14. The method of claim 9 in which said bar code of the bag is carried on a flap of said bag which is spaced from the blood products carried therein, said at least one preformed aperture being also defined in said flap.

15. A method of medically treating a blood product which comprises placing a flexible, flat collapsible bag having walls into a housing, said bag holding a blood product, the walls of said bag being made of a plastic material which permits the desired medical treatment to be effected on the blood product, said bag carrying a bar code relating to the contents of said bag;

said method comprising;

positioning the bag so that the bar code carried by the bag is in position to be read by a bar code reader carried with the housing;

automatically reading, via the bar code reader, the bar code of said bag within said housing;

via software (a) automatically confirming by said bar code if the bag is approved for said medical treatment, (b) automatically performing said medical treatment on the bag if the bag is approved, but (c) automatically terminating the process without medical treatment if the bag carries a bar code indicating that the bag is not approved.

16. The method of claim 15 in which at least one pin positioned within said housing is passed through a preformed aperture of said bag, said aperture being spaced from the interior of said bag.

17. The method of claim 16 in which the bar code of said bag is carried on a flap of said bag which is spaced from the contents of said bag.