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Electrotransport drug delivery reservoirs containing inert fillers

  • US 6,246,904 B1
  • Filed: 11/07/1997
  • Issued: 06/12/2001
  • Est. Priority Date: 12/17/1996
  • Status: Expired due to Term
First Claim
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1. An electrotransport agent delivery device, comprising a donor electrode, a counter electrode and a source of electrical power adapted to be electrically connected to the donor and counter electrodes, wherein the donor electrode is electrically connected to a donor reservoir having a predetermined volume (V) and being comprised of a polymeric matrix containing a predetermined quantity (q) of a therapeutic agent to be delivered, the polymeric matrix also containing an inert filler material having substantially no tendency to interact with the agent, the inert filler being present in the matrix in a form which allows electrotransport of the agent through and from the reservoir to a patient body surface, the inert filler material being present in the polymeric matrix in an amount which achieves a concentration (ρ

  • ) of therapeutic agent in the matrix which exceeds q/V.

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