Universal computer assisted diagnosis

• US 6,247,004 B1
• Filed: 08/20/1999
• Issued: 06/12/2001
• Est. Priority Date: 08/18/1997
• Status: Expired due to Fees

• Current Assignee: Connectance, Inc.
• Original Assignee: Nabil W. Moukheibir
• Inventors: Moukheibir, Nabil W.
• Primary Examiner(s): Powell, Mark R.
• Assistant Examiner(s): KHATRI, ANIL
• Application Number:
  US09/378,440
• Time in Patent Office: 662 Days
• Field of Search: 706/45, 706/46, 706/47, 706/50, 600/300, 705/2, 707/1, 707/100, 707/200
• US Class Current: 706/46
• CPC Class Codes: G16H 40/63 for local operation
• CPC Class Codes: G16H 50/20 for computer-aided diagnosis, e.g. based on medical expert systems
• CPC Class Codes: G16H 70/60 relating to pathologies

Abstract

A method is provided which facilitates diagnosis of any describable condition or event. One example is specialty related medical conditions and diseases. The method first provides, in a computer accessible data base, for the creation of a plurality of master maps using keywords and a new diagnostic mapping language. Then a medical description of a patient'"'"'s history and physical information is input into a computer using simple medical file language. Chemical and test data information are displayed on the screen to prompt entry of available chemical and test data for the patient, and this may also be practiced for imaging selections which may be in a yes/no/empty format. Using a computer processor a data base of specialty medical information is searched to determine the degree of similarity between the information entered and the master maps, and the possible diagnoses are ranked based on the degree of similarity. The three most probable diagnoses are displayed on a monitor, such as in the form of horizontal bar graphics which bar graph is a first color in a horizontal field and the diagnosis corresponding to the bar graph is in the same field in a different color. Biopsy and imaging icons, which are miniature versions of actual biopsies or images exemplary of the disease or condition, may be selected. The computer and data base may be used in a catalog mode, in addition to the above-description analytical mode, by displaying on the screen options relating to the biopsy, imaging, management (a condensed opinion and textual information about how to understand and treat a particular disease or medical condition) and bibliography (a listing of suggested readings).

Claims

1. A method of creating a computer searchable data base for use with a computer having a display screen, input device, and processor, for ultimately diagnosing a condition or event from a large plurality of possible conditions or events or events that may exist in a particular art, said method comprising the steps of:

(a) determining what key words describe the characteristic features of each of the possible conditions or events of the large plurality of possible conditions or events;

(b) creating in computer searchable form a master map for each of the large plurality of possible conditions or events using the key words from step (a) that accurately describe each of the conditions or events, to provide a data base containing all the master maps; and

(c) providing search access to the master maps data base in the computer so that by a user manipulating the input device to provide a narrative containing some of the key words from step (a), the computer processor will compare the key words input to the key words associated with each master map to determine what conditions or events represented by master maps have the highest degree of similarity with the narrative input, and display those conditions or events on the display screen.

2. A method as recited in claim 1 wherein step (a) is practiced by dividing the key words into three different classifications of words, main words that describe the most important feature of a sentence that accurately describes an aspect of a condition or event, descriptor words that further describe a main word by adding a qualification, and complements that further describe a descriptor by adding a qualification;

and wherein step (b) is practiced by providing a plurality of distinctly searchable elements for each condition or event, each element including at least a main word, and where they accurately exist, a descriptor and complement associated with that main word.

3. A method as recited in claim 2 wherein the art is a medical specialty, and wherein the conditions or events are possible diseases or medical conditions of that medical specialty, and wherein the main words describe the anatomy or body fluid or tissue involved with the disease or medical condition to be addressed, the descriptor describes the deviation from normal of the main word, and the complement adds specificity to the main or descriptor words.

4. A method as recited in claim 2 wherein steps (a) and (b) are also practiced by assigning key words to laboratory test results related to each condition, including the name of a test, the normal numerical value of the test results if the condition doesn'"'"'t exist, and a flag indicating that the value of inputted data is above normal, below normal, or text including at least one of normal, abnormal, positive, negative, absent, or present.

5. A method as recited in claim 1 wherein steps (a) and (b) are also practiced by assigning key words to laboratory test results related to each condition, including the name of a test, the normal numerical value of the test results if the condition doesn'"'"'t exist, and a flag indicating that the value of inputted data is above normal, below normal, or text including at least one of normal, abnormal, positive, negative, absent, or present.

6. A method as recited in claim 1 wherein steps (a) and (b) are practiced by assigning either a yes or no to individual imaging possibilities related to a particular condition or event.

7. A method as recited in claim 1 comprising the further steps of providing zoom and marking functions within a displayed biopsy or image corresponding to a highlighted diagnosis upon selection of the biopsy or imaging icons.

8. A method as recited in claim 1 wherein step (c) is practiced by placing the master maps data base on a CD along with biopsy images, medical imaging images, or both biopsy images and medical imaging images, associated with a plurality of the master maps, the images capable of display on the display screen by the user manipulating the input device.

9. A method as recited in claim 1 where (c) is further practiced by displaying on the display screen at least the two conditions or events represented by master maps having the highest degree of similarity with the narrative input.

10. A method of diagnosing a condition or event from a large plurality of possible conditions or events that may exist in a particular art, each condition or event being provided in a master map which describes that condition or event using a plurality of art specific key words, said method practiced using a computer having a display screen, input device, and processor, said method comprising the steps of:

(a) providing search access to the master maps data base in the computer so that by a user manipulating the input device to provide a narrative containing some of the key words, the computer processor will compare the key words input to the key words associated with each master map;

(b) using the input device, inputting a narrative description that can facilitate diagnosis, the narrative description using some of the key words;

(c) using the input device, activating the computer processor to recognize the key words from the input narrative description, compare the key words to the key words of each of the master maps, to determine what conditions or events represented by master maps have the highest degree of similarity with the narrative input; and

(d) displaying on the display screen at least the two conditions or events represented by master maps having the highest degree of similarity with the narrative input.

11. A method as recited in claim 10 wherein each master map has key words divided into three different classifications of words, main words that describe the most important feature of a sentence that accurately describes an aspect of the condition or event associated with that master map, descriptor words that further describe a main word by adding a qualification, and complement words that further describe a descriptor by adding a qualification, each master map having a plurality of distinctly searchable elements for each condition or event, each element including at least a main word, and where they accurately exist, a descriptor and complement associated with that main word, some of the key words being weighted but the majority of key words having a common value;

and wherein step (c) is practiced by counting the weighted number of key words within searchable elements in each master map which also appear in the narrative input in step (b), the master map having the highest weighted number of key words within searchable elements being determined as having the highest degree of similarity, and the condition or event associated with that master map therefore considered to have the highest probability of being the correctly diagnosed condition or event.

12. A method as recited in claim 11 wherein each master map has assigned to each of the elements one of at least two possible logics, a first logic that requires a main and at least a descriptor to also be present before the element is recognized by the processor when searching the data base, and a second logic that requires only the main to be present, but recognizes a descriptor and complement if present;

and wherein step (c) is practiced by;

searching with the processor for those first logic elements identified as corresponding to both main and descriptor key words in the narrative description before selection, and then counting the main, descriptor, and complement words associated with those first logic elements; and

searching with the processor for those second logic elements identified as corresponding to a main key word in the narrative description and then counting the main words, and any descriptor or complement words associated therewith, of the second logic elements.

13. A method as recited in claim 10 wherein a plurality of possible conditions or events or possible diseases or medical conditions in a specialty, and steps (a) through (c) are practiced by a specialist physician.

14. A method as recited in claim 13 wherein the data base provided in step (a) also includes key words assigned to laboratory test results related to each medical condition or disease, including the name of a test, the normal numerical value of the test results, and a flag indicating that the value of inputted data is above normal, below normal, or text including at least one of normal, abnormal, positive, negative, absent, or present;

and values of yes or no assigned to individual imaging possibilities related to a particular medical condition or disease; and

wherein step (c) is also practiced by searching the relevant laboratory test results and imaging values.

15. A method as recited in claim 14 wherein steps (a) and (b) are practiced by assigning either a yes or no to individual imaging possibilities related to a particular condition or event.

16. A method of facilitating diagnosis of medical conditions using a computer having a display screen, an input device, and processor, and connected to a data base of detailed medical information including a plurality of master maps, one for each known medical condition to be evaluated, said method, comprising the steps of:

(a) using the keyboard, inputting into the computer a medical description of a patient'"'"'s history and physical information, including signs and symptoms, using simple medical file language;

(b) displaying chemical and test data information on the screen to prompt entry of available chemical and test data for the patient;

(c) using the input device, entering all relevant chemical and test data in response to the prompt from step (b);

(d) displaying a plurality of imaging option selections on the screen in yes/no format;

(e) using the input device, entering known imaging data in yes/no format in response to the display in step (d);

(f) using the processor, searching the data base of detailed medical information to determine the degree of resemblance between the data input and each of the master maps, and ranking possible diagnoses based upon the degree of resemblance; and

(g) displaying on the screen at least the two most probable diagnoses based upon the degree of resemblance determined in step (f), and in order of the degree of resemblance.

17. A method as recited in claim 16 wherein step (g) is practiced to display possible diagnoses in the form of horizontal bar graphics in which the bar graph is a first color in a horizontal field and the diagnosis corresponding to the bar graph is also in the horizontal field in a second color, different than the first color, the length of the bar graphics being proportioned to the probability of the diagnosis.

18. A method as recited in claim 16 comprising the further step (h) of displaying at least one of biopsy and imaging icons that may be selected to provide pictorial information displayed on the screen corresponding to a selected one of the diagnoses displayed on the screen.

19. A method as recited in claim 16 comprising the further steps, during the practice of at least one of steps (b) and (c), and steps (d) and (e), of displaying an alphabetical keyboard image on the screen, and using the input device selecting a letter from the alphabetical keyboard image to display on the screen listing of chemical or test data, or imaging options, starting with the letter selected.

20. A method of facilitating diagnosis of specialty related medical conditions using a computer having a display screen, input device, and processor, and connected to a data base of specialty medical information, comprising the steps of:

(a) using the input device, inputting into the computer a medical description of a patient'"'"'s history and physical information, including signs and symptoms, and any relevant available chemical and test data and imaging information;

(b) using the processor searching the data base of specialty medical information to determine the most likely possible diagnosis;

(c) displaying on the screen at least the two most probable diagnoses located in step (b); and

(d) substantially simultaneously with step (c), displaying on the screen textual information, and at least one of biopsy and imaging icons, corresponding to a selected diagnosis, the biopsy and imaging icons, if selected, displaying on the screen actual pictorial representations of actual biopsies or images associated with the diagnosis selected.

21. A method as recited in claim 20 comprising the further step (e) of displaying on the screen in comparative format biopsy or imaging pictorial representations corresponding to more than one diagnosis from step (c).

22. A method of providing specific categorized information relating to medical information using a computer having a display screen and input device, and connected to a data base of medical information, comprising the steps of:

(a) displaying on the screen the options of biopsy, imaging, management, and bibliography relating to a particular disease or medical condition;

(b) using the input device, selecting the biopsy option to display pictorially on the screen actual biopsy pictorial representations of the particular disease or medical condition;

(c) using the input device selecting the imaging options to display pictorially on the screen actual imaging pictorial representations of the particular disease or medical condition;

(d) using the input device selecting the management option to display on the screen a condensed opinion and textual information about how to understand and treat the particular disease or medical condition; and

(e) using the input device selecting the bibliography option to display on the screen a listing of suggested readings related to pathogenesis and therapy for the particular disease or condition.

23. A method as recited in claim 22 wherein steps (b) and (c) are further practiced by displaying zoom and marking functions on the screen, and using the input device selecting the zoom or marking functions to effect an increase or decrease in the size of any particular area of the biopsy or imaging pictorial representations displayed, or to effect marking of any desired portion of the biopsy or imaging pictorial representations displayed.

24. A method of providing specific categorized information relating to medical information, using a computer having a display screen, an input device, a CD ROM, and a data base on a CD, comprising the steps of:

(a) displaying on the screen an analytical option and a catalog option;

(b) using the input device, selecting the analytical option to bring up screens allowing the input of a patient'"'"'s history and physical information, including signs and symptoms, chemical and test data, and imaging data, that may contribute to an accurate differential diagnosis;

(c) using the input device entering the known information from step (b);

(d) with the computer searching the CD data base to compare the information entered with known disease and medical condition information contained in the data base;

(e) using the input device selecting the catalog option to display on the screen options relating to an opinion about how to understand and treat a disease or condition, reading material relating to a selected disease or condition, and at least one of biopsy and imaging information relating to a selected disease or condition; and

(f) using the input device, selectively displaying the at least one of biopsy and imaging information from the CD in pictorial form on the display screen, which biopsy or imaging information relates to a selected disease or condition.

25. A method as recited in claim 24 wherein steps (e) and (f) are practiced to display both biopsy and imaging information relating to a selected disease or condition.