Single use container for dispensing separately housed sterile compositions

• US 6,247,617 B1
• Filed: 12/13/1999
• Issued: 06/19/2001
• Est. Priority Date: 12/13/1999
• Status: Expired due to Fees

• Current Assignee: Richard Allen Clyde, Steven Frank Simmons
• Original Assignee: Richard Allen Clyde, Steven Frank Simmons
• Inventors: Simmons, Steven Frank, Clyde, Richard Allen
• Primary Examiner(s): JACYNA, J CASIMER
• Application Number:
  US09/459,709
• Time in Patent Office: 554 Days
• Field of Search: 222/94, 222/145.1, 222/541.1, 222/541.6, 222/541.9
• US Class Current: 222/94
• CPC Class Codes: B65D 1/0238 Integral frangible closures
• CPC Class Codes: B65D 81/3283 Cylindrical or polygonal containers, e.g. bottles, with two or more substantially axially offset, side-by-side compartments for simultaneous dispensing B65D35/22, B65D35/242, B65D81/3227, B65D81/325 take precedence

Abstract

A single use container for accurately dispensing separately housed sterile compositions with minimal contact to non-sterile surfaces of the container is disclosed. Embodiments include a container having a first and second chamber within the container for housing a first and second sterile composition. Each chamber has an angled channel which defines an axis for directing the sterile composition from their respective chambers. The angled channels are directed toward each other and are so angled as to minimize contact of the escaping sterile compositions with a non-sterile surface of the container, e.g. the tip. A plurality of tear-off closures seal the angled channels to prevent the sterile compositions from escaping from their respective chambers and a tab portion is provided joining the plurality of closures. Removing the tab portion causes all of the solid closures to be removed in a single action.

Claims

1. A single use container for dispensing separately housed sterile compositions and for minimizing contact of the sterille compositions with a non-sterile surface of the container, the container comprising:

a first chamber within the container for housing a first sterile composition having a first angled channel for directing the first sterile composition from the first chamber;

a second chamber within the container for housing a second sterile composition having a second angled channel for directing the second sterile composition from the second chamber, wherein the first and second angled channels are directed toward each

a plurality of tear-off solid closures sealing the channels to prevent the sterile compositions from escaping; and

a tab portion joining the plurality of tear-off solid closures, wherein removing the tab portion causes all of the tear-off solid closures to be removed in a single action and permit the sterile compositions housed in their respective chambers to escape through their respective angled channels and combine at a point distal from the container wherein the first and second angled channels form an angle which prevents the combined compositions from substantially contacting an outer, non-sterile surface of the container and prevents contamination to the sterile compositions,

wherein the container comprises a flexible sterilizable material.

2. The container of claim 1, wherein the angled channels form an angle no greater than about 180 degrees.

3. The container of claim 1, wherein the angled channels form an angle no greater than about 60 degrees.

4. The container of claim 1, wherein the container is made of a flexible polymer selected from the group consisting of polyamides, polyesters, polyethers, polyurethanes, polyolefins, random or block copolymer thereof, or blends thereof.

5. The container of claim 1, wherein the container is made of a flexible polyolefin.

6. The container of claim 1, wherein the first and second chambers house compositions that comprise different active agents.

7. The container of claim 1, wherein the first and second chamber individually house a volume of about 0.25 cubic centimeter to about 10 cubic centimeters.

8. The container of claim 1, wherein the first chamber contains a different volume from the second chamber.

9. The container of claim 4, further comprising a third chamber within the body for containing a third sterile composition, wherein the third chamber has a third angled channel for directing the third sterile composition from the third chamber.

10. The container of claim 4, comprising a first sterile composition in the first chamber and a second sterile composition in the second chamber.

11. The container of claim 10 wherein the first and second sterile compositions are different.

12. The container of claim 1, comprising one or more pharmaceutically active compositions.

13. The container of claim 1, comprising a bronchodilator solution.

14. The container of claim 1, comprising one or more compositions.