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Pharmaceutical aerosol formulation containing a particulate medicament, a propellant and substantially free of a surfactant

  • US 6,251,368 B1
  • Filed: 06/17/1997
  • Issued: 06/26/2001
  • Est. Priority Date: 12/12/1991
  • Status: Expired due to Fees
First Claim
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1. A pharmaceutical aerosol formulation which comprises particulate medicament selected from the group consisting of salmeterol, salbutamol, fluticasone propionate, beclomethasone dipropionate and physiologically acceptable salts and solvates thereof and 1,1,1,2-tetrafluoroethane as propellant, which formulation is substantially free of surfactant and with the proviso that when said formulation consists essentially of salbutamol and 1,1,1,2-tetrafluoroethane in a weight ratio of 0.05:

  • 18, said salbutamol is present in the form of a physiologically acceptable salt.

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