Devices and methods for detecting target molecules in biological samples
First Claim
1. A cylindrical device for detecting the presence, or absence, of a target molecule in a biological sample contained in a sample collection unit, the device comprising a biocompatible attachment and at least one reaction chamber, wherein the reaction chamber comprises at least one breakable barrier and at least one compartment containing a primer or probe for detecting the presence, or absence, of the target molecule, and further comprising within a cylindrical apparatus capable of circular rotation about a central axis, wherein the apparatus comprises a piston or plunger capable of ingress or egress through the at least one compartment.
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Accused Products
Abstract
Devices and methods for detecting the presence, or absence of the presence of at least one target molecule employing a receptacle housing a reaction chamber comprised of at least one compartment containing suitable reagents for the detection of the target molecule are disclosed.
200 Citations
35 Claims
- 1. A cylindrical device for detecting the presence, or absence, of a target molecule in a biological sample contained in a sample collection unit, the device comprising a biocompatible attachment and at least one reaction chamber, wherein the reaction chamber comprises at least one breakable barrier and at least one compartment containing a primer or probe for detecting the presence, or absence, of the target molecule, and further comprising within a cylindrical apparatus capable of circular rotation about a central axis, wherein the apparatus comprises a piston or plunger capable of ingress or egress through the at least one compartment.
- 27. A cylindrical device for detecting the presence, or absence, of a target molecule in a biological fluid contained in a sample collection unit, the device comprising a biocompatible attachment and at least one reaction chamber, wherein the reaction chamber comprises at least one breakable barrier and at least one compartment containing an amplification primer to assist in detecting the presence, or absence, of the target molecule, and further comprising within a cylindrical apparatus capable of circular, rotation about a central axis, wherein the apparatus comprises a piston or plunger capable of ingress or egress through the at least one compartment.
- 31. A cylindrical device for detecting the presence, or absence, of a target molecule in a biological fluid contained in a sample collection unit, the device comprising a biocompatible attachment and at least one reaction chamber, wherein the reaction chamber comprises at least one breakable barrier and at least one compartment containing a probe for detecting the presence, or absence, of the target molecule, and further comprising within a cylindrical apparatus capable of circular rotation about a central axis, wherein the apparatus comprises a piston or plunger capable of ingress or egress through the at least one compartment.
Specification