Cardiac assist system and method thereof

• US 6,254,525 B1
• Filed: 11/02/1999
• Issued: 07/03/2001
• Est. Priority Date: 11/04/1998
• Status: Expired due to Fees

• Current Assignee: Cardio Technologies, Inc.
• Original Assignee: Cardio Technologies, Inc.
• Inventors: Reinhardt, Robert W., Levin, Howard R.
• Primary Examiner(s): Schaetzle, Kennedy
• Application Number:
  US09/432,518
• Time in Patent Office: 609 Days
• Field of Search: 600/16, 600/17, 607/2, 607/3, 607/4, 607/5, 623/3.11, 623/3.16, 623/3.21, 623/3.28, 623/3.27
• US Class Current: 600/17
• CPC Class Codes: A61M 2205/33 Controlling, regulating or measuring
• CPC Class Codes: A61M 2205/3303 Using a biosensor
• CPC Class Codes: A61M 60/148 in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices
• CPC Class Codes: A61M 60/191 mechanically acting upon the outside of the patient's native heart, e.g. compressive structures placed around the heart
• CPC Class Codes: A61M 60/289 Devices for mechanical circulatory actuation assisting the residual heart function by means mechanically acting upon the patient's native heart or blood vessel structure, e.g. direct cardiac compression [DCC] devices
• CPC Class Codes: A61M 60/468 the force acting on the actuation means being hydraulic or pneumatic
• CPC Class Codes: A61M 60/515 Regulation using real-time patient data
• CPC Class Codes: A61M 60/839 of devices for mechanical circulatory actuation
• CPC Class Codes: A61N 1/3621 for treating or preventing abnormally high heart rate

Abstract

A cardiac assist system includes a sensor that is operative to sense the electrical activity of a patient'"'"'s heart. The sensed electrical activity is processed to determine the onset of ventricular contraction. A compressive force from a ventricular assist device is applied to the ventricles during at least a portion of the heart'"'"'s ventricular contraction. The cardiac assist system also includes an electrical stimulating system. Thus, in the event the heart begins to fibrillate, the electrical stimulating system is actuated to apply stimulating pulses to the heart.

Claims

1. A system for assisting a heart to pump blood, the system comprising:

a ventricular assist device having an interior surface and including an inflatable bladder that is operative to apply pressure to at least a portion of the heart;

a source of pressurized fluid connected to the inflatable bladder and operative to inflate the bladder;

at least one electrical sensor configured to be positioned in contact with the heart when the ventricular assist device is engaged to the heart, the electrical sensor being operative to sense electrical activity of the heart and to generate corresponding electrical signals; and

a controller electrically connected to the sensor and to the source of pressurized fluid, the controller being programmed to receive the electrical signals from the sensor, process the electrical signals to determine the onset of ventricular contraction in the heart, and control the source of pressurized fluid to supply pressurized fluid to the bladder to inflate the bladder at a time synchronous with the ventricular contraction of the heart;

wherein the sensor comprises an electrode operative to sense electrical activity of the heart and to generate a corresponding electrical signal;

the sensor defines a stimulating electrode connected to the interior surface of the ventricular assist device to contact the heart when the ventricular assist device is placed over the heart, the stimulating electrode being responsive to receipt of electrical stimulating energy to apply the energy to the heart, the stimulating electrode further being operative to sense electrical activity of the heart; and

further including at least one pick-up electrode external of the ventricular assist device and electrically connected to the stimulating electrode, the pick-up electrode being operative to collect electrical energy and to conduct the electrical energy to the stimulating electrode.

2. The system of claim 1, wherein the pick-up electrode is mounted on an exterior surface of the ventricular assist device.

3. The system of claim 1, further including plural pick-up electrodes and plural stimulating electrodes, the pick-up electrodes being electrically connected to the respective stimulating electrodes.

4. The system of claim 1, wherein the pick-up electrode is spaced from the ventricular assist device.

5. The system of claim 1, wherein the ventricular assist device further comprises a suction membrane configured to engage the heart, and the stimulating electrode is mounted on the suction membrane.

6. The system of claim 1, wherein the stimulating electrode is connected to a source of stimulating energy via an electrical lead.

7. A method of assisting a heart to pump blood, comprising:

engaging a ventricular assist device to at least a portion of the heart;

sensing the electrical activity of the heart;

determining when the ventricles of the heart are contracting;

applying pressure to at least a portion of the ventricles of the heart at a time synchronous with the heart'"'"'s natural contraction of the ventricles; and

applying defibrillation energy to a patient from a location external to the patient, when the patient'"'"'s heart is fibrillating;

receiving the externally applied energy at one or more electrodes inside the patient'"'"'s body; and

conducting the received energy to one or more electrodes in contact with the patient'"'"'s heart to apply the energy to the heart.

8. The method of claim 7, wherein the step of applying defibrillation energy includes using defibrillation paddles.

9. The method of claim 7, wherein the step of receiving the externally applied energy includes using a pair of pick-up electrodes.

10. The method of claim 7, wherein the step of conducting the received energy includes using a pair of stimulation electrodes in contact with the heart.

11. The method of claim 7, wherein the step of determining when the ventricles are contracting comprises detecting a magnitude of electrical activity of the heart, comparing the magnitude of the detected electrical activity with a preselected threshold value, and determining whether the magnitude of the detected electrical activity exceeds the preselected threshold value.

12. A system for assisting a heart to pump blood and for applying stimulating pulses to the heart, the system comprising:

a ventricular assist device including an inflatable bladder that is operative to apply pressure to at least a portion of the heart;

a source of pressurized fluid connected to the inflatable bladder and operative to inflate the bladder;

at least one electrical sensor in contact with the ventricular assist device and configured to be positioned in contact with the heart when the ventricular assist device is engaged to the heart, the electrical sensor being operative to sense electrical activity of the heart and to generate corresponding electrical signals;

a controller electrically connected to the sensor and to the source of pressurized fluid, the controller being programmed to receive the electrical signals from the sensor, determine from the electrical signals when the heart enters into a ventricular contraction stage, and control the source of pressurized fluid to supply pressurized fluid to the bladder to inflate the bladder during at least a portion of the ventricular contraction of the heart;

a stimulating electrode in contact with the ventricular assist device and configured to be positioned in contact with the heart when the ventricular assist device is engaged to the heart; and

a source of stimulating pulses in communication with the stimulating electrode and operative to generate electrical stimulating pulses and transmit the stimulating pulses to the stimulating electrode for application to the heart;

wherein the source of stimulating pulses comprises at least one pick-up electrode external of the ventricular assist device and electrically connected to the stimulating electrode, the pick-up electrode being operative to collect externally applied electrical energy and conduct the electrical energy to the stimulating electrode.

13. The system of claim 12, wherein the sensor comprises an electrode operative to sense electrical activity of the heart and to generate a corresponding electrical signal.

14. The system of claim 12, wherein the sensor defines the stimulating electrode.

15. The system of claim 12, wherein the pick-up electrode is mounted on an exterior surface of the ventricular assist device.

16. The system of claim 12, further including plural pick-up electrodes and plural stimulating electrodes, the pick-up electrodes being electrically connected to the respective stimulating electrodes.

17. The system of claim 12, wherein the pick-up electrode is spaced from the ventricular assist device.

18. The system of claim 12, wherein the ventricular assist device further comprises a suction membrane configured to engage the heart, and the stimulating electrode is mounted on the suction membrane.