Flow-through peritoneal dialysis systems and methods with on-line dialysis solution regeneration
First Claim
1. A system for conducting peritoneal dialysis comprisinga pumping assembly to circulate peritoneal dialysis solution through a peritoneal cavity to perform peritoneal dialysis including a inlet branch to convey peritoneal dialysis solution into the peritoneal cavity and an outlet branch to withdraw peritoneal dialysis solution from the peritoneal cavity, and a regeneration assembly coupled in-line between the inlet and outlet branches, the regeneration assembly including a source of a regeneration solution that carries at least one agent for regenerating spent peritoneal dialysis solution, and a porous membrane having a first side, along which peritoneal dialysis solution is circulated by the pumping assembly from the outlet branch to the inlet branch, and a second side, along which the regeneration solution is circulated, the porous membrane being configured to transport waste from spent peritoneal dialysis solution into the regeneration solution and to transport the regenerating agent from the regeneration solution into spent peritoneal dialysis solution, the regeneration assembly operating to create from peritoneal dialysis solution in the outlet branch, a regenerated dialysis solution for conveyance through the inlet branch into the peritoneal cavity.
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Accused Products
Abstract
Peritoneal dialysis is performed by circulating peritoneal dialysis solution through a peritoneal cavity by conveying peritoneal dialysis solution through an inlet branch into the peritoneal cavity and by withdrawing peritoneal dialysis solution through an outlet branch from the peritoneal cavity. Peritoneal dialysis solution in the outlet branch is conveyed along a first side of a porous membrane while conveying a regeneration solution containing at least one regenerating agent along a second side of the porous membrane. The membrane is configured to transport the regenerating agent into the peritoneal dialysis solution while transporting waste from the peritoneal dialysis solution into the regeneration solution, thereby creating a regenerated peritoneal dialysis solution. The regenerated peritoneal dialysis solution is circulated through the inlet branch into the peritoneal cavity.
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Citations
59 Claims
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1. A system for conducting peritoneal dialysis comprising
a pumping assembly to circulate peritoneal dialysis solution through a peritoneal cavity to perform peritoneal dialysis including a inlet branch to convey peritoneal dialysis solution into the peritoneal cavity and an outlet branch to withdraw peritoneal dialysis solution from the peritoneal cavity, and a regeneration assembly coupled in-line between the inlet and outlet branches, the regeneration assembly including a source of a regeneration solution that carries at least one agent for regenerating spent peritoneal dialysis solution, and a porous membrane having a first side, along which peritoneal dialysis solution is circulated by the pumping assembly from the outlet branch to the inlet branch, and a second side, along which the regeneration solution is circulated, the porous membrane being configured to transport waste from spent peritoneal dialysis solution into the regeneration solution and to transport the regenerating agent from the regeneration solution into spent peritoneal dialysis solution, the regeneration assembly operating to create from peritoneal dialysis solution in the outlet branch, a regenerated dialysis solution for conveyance through the inlet branch into the peritoneal cavity.
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42. A method for conducting peritoneal dialysis comprising steps of
(i) circulating peritoneal dialysis solution through a peritoneal cavity to perform peritoneal dialysis by conveying peritoneal dialysis solution through an inlet branch into the peritoneal cavity and by withdrawing peritoneal dialysis solution through an outlet branch from the peritoneal cavity, (ii) during at least a portion of step (i), conveying peritoneal dialysis solution in the outlet branch along a first side of a porous membrane while conveying a regeneration solution containing at least one regenerating agent along a second side of the porous membrane, the membrane being configured to transport the regenerating agent into the peritoneal dialysis solution while transporting waste from the peritoneal dialysis solution into the regeneration solution, thereby creating a regenerated peritoneal dialysis solution, and (iii) during at least a portion of step (i), circulating the regenerated peritoneal dialysis solution through the inlet branch into the peritoneal cavity.
Specification