Device for administering an injectable product

• US 6,258,068 B1
• Filed: 05/14/1999
• Issued: 07/10/2001
• Est. Priority Date: 05/15/1998
• Status: Expired due to Term

• Current Assignee: TecPharma Licensing AG (Ypsomed Holding AG)
• Original Assignee: Disetronic Licensing Ag (Roche Holding AG)
• Inventors: Heiniger, Hanspeter, Hostettler, Peter, Kirchhofer, Fritz, Steck, Jürg, Jost, Stephan
• Primary Examiner(s): NGUYEN, ANH TUAN TUONG
• Application Number:
  US09/311,434
• Time in Patent Office: 788 Days
• Field of Search: 604/131, 604/133, 604/134, 604/135, 604/208, 604/181, 604/187, 604/154, 128/DIG.1
• US Class Current: 604/208
• CPC Class Codes: A61M 2005/2013 triggering of discharging means by contact of injector with patient body
• CPC Class Codes: A61M 2005/206 With automatic needle insertion
• CPC Class Codes: A61M 2005/2073 preventing premature release, e.g. by making use of a safety lock
• CPC Class Codes: A61M 2005/2086 having piston damping means, e.g. axially or rotationally acting retarders
• CPC Class Codes: A61M 2005/2407 from the rear
• CPC Class Codes: A61M 2005/2488 via rotation, e.g. threads or bayonet
• CPC Class Codes: A61M 5/2033 Spring-loaded one-shot injectors with or without automatic needle insertion multishot dosing syringes A61M5/31525, needle insertion only A61M5/3287
• CPC Class Codes: A61M 5/24 Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic ampoules or carpules A61J1/06
• CPC Class Codes: A61M 5/315 Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
• CPC Class Codes: A61M 5/3202 Devices for protection of the needle before use, e.g. caps A61M5/50 takes precedence; for infusion spikes A61M5/1626; protectors for sharps A61B50/3001
• CPC Class Codes: A61M 5/3204 Needle cap remover, i.e. devices to dislodge protection cover from needle or needle hub, e.g. deshielding devices
• CPC Class Codes: A61M 5/3257 Semi-automatic sleeve extension, i.e. in which triggering of the sleeve extension requires a deliberate action by the user, e.g. manual release of spring-biased extension means
• CPC Class Codes: A61M 5/326 Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
• CPC Class Codes: A61M 5/48 having means for varying, regulating, indicating or limiting injection pressure A61M5/142 takes precedence ; monitoring pressure in infusion systems A61M5/16854
• CPC Class Codes: A61M 5/488 Limiting injection pressure
• CPC Class Codes: Y10S 128/01 Motorized syringe

Abstract

The invention provides a injection device for administering an injectable product, including a base section adapted to receive a container from which a product dose is dispensed through a needle by displacement of a piston in the container, and a drive unit including a driven member, a drive element and a damping arrangement, the drive unit for applying a force to advance the piston in the container to dispense a dose, wherein the damping arrangement generally counteracts the drive force and counter forces. The invention also encompasses a needle safety sleeve and a blocking structure for use with injection devices.

Claims

1. A device for administering an injectable product, comprising:

a) a base section;

b) a container arranged in the base section from which a product dose is dispensed through a needle by displacement of a piston associated with the container;

c) a drive unit, comprising a driven member and a drive element, the drive element applying a drive force on said driven member upon actuating the drive unit, by which drive force on said drive member said driven member is displaced in the direction of the piston, thus advancing said piston within said container; and

d) a chamber open to the atmosphere for creating a damping force, wherein a portion of the driven member forms at least one wall of the chamber, said chamber comprising a port open to the atmosphere for allowing air to flow in and out of said chamber, whereby, when advancing said driven member the chamber changes in volume, said port allowing for a delayed pressure compensation accompanying the change in volume thereby creating the damping force, said damping force interacting with the drive force and counter forces associated with the use of the device.

2. The device as set forth in claim 1, wherein the damping force decreases in the course of displacement of said piston.

3. The device as set forth in claim 1, wherein said chamber is a low-pressure chamber.

4. The device as set forth in claim 1, wherein a stripper is carried on the device, which stripper can be moved back and forth in a longitudinal direction of the needle in order to strip off a needle safety cap applied to the needle, said stripper carried on the device in such a way as to allow said stripper to remain on the device during an injection and to be pushed back for insertion of said needle.

5. The device as set forth in claim 1, wherein a needle safety sleeve is displaceably arranged in relation to said base section from a base position in which it generally surrounds the needle to an administering position, in which said needle projects beyond said needle safety sleeve, said needle safety sleeve being blockable against displacement in a direction towards the administering position in relation to said base section.

6. The device as set forth in claim 1, wherein the device is an auto-injection device, said container, including the needle attached to it, being displaceable in relation to said base section from a base position to an administering position for insertion of the needle, and, in the base position, said container being blocked against advancement by a releaseable engagement of a blocking means.

7. The device as set forth in claim 6, wherein said blocking means selectively blocks said container against advancement and said needle safety sleeve against retraction.

8. A device for administering an injectable product, comprising:

a) a base section;

b) a container arranged in the base section from which a product dose is dispensed through a needle by displacement of a piston associated with the container;

c) a drive unit, comprising a driven member and a drive element, the drive element applying a drive force on said driven member upon actuating the drive unit, by which drive force said driven member is displaced in the direction of the piston, thus advancing said piston within said container; and

d) a contact pressure element for generating a damping force, said contact pressure element transmitting a clamping force between said driven member and a counter element, wherein one of said driven member and said counter element provides a contact pressure surface for said contact pressure element, extending in a forward direction of said driven member so as to cause the clamping force to decrease in the course of advancement.

9. The device as set forth in claim 8, wherein said contact pressure element is a pliable ring, arranged in a gap formed between said driven member and said counter element, said gap widening in the course of advance of said driven member.

10. The device as set forth in claim 8, wherein the damping force decreases in the course of displacement of said piston.

11. The device as set forth in claim 8, wherein a stripper is carried on the device, which stripper can be moved back and forth in a longitudinal direction of the needle in order to strip off a needle safety cap applied to the needle, said stripper carried on the device in such a way as to allow said stripper to remain on the device during an injection and to be pushed back for insertion of said needle.

12. The device as set forth in claim 8, wherein a needle safety sleeve is displaceably arranged in relation to said base section from a base position in which it generally surrounds the needle to an administering position, in which said needle projects beyond said needle safety sleeve, said needle safety sleeve being blockable against displacement in a direction towards the administering position in relation to said base section.

13. The device as set forth in claim 8, wherein the device is an auto-injection device, said container, including the needle attached to it, being displaceable in relation to said base section from a base position to an administering position for insertion of the needle, and, in the base position, said container being blocked against advancement by a releaseable engagement of a blocking means.

14. A device for administering an injectable product, comprising:

a base section;

a drive unit, comprising at least a driven member and a drive element, the drive element applying a drive force on said driven member, whereby the driven member is displaced toward the base section; and

a damping arrangement comprising a chamber wherein the a portion of the driven member forms at least one wall of the chamber, the chamber comprising a port open to the atmosphere so air can flow in and out of the chamber, whereby advancing said driven member changes the volume of the chamber, said port allowing for a delayed pressure compensation accompanying the change in volume thereby generating a damping force.

15. The device according to claim 14, further comprising a needle safety sleeve displaceably arranged in relation to said base section from a base position in which it generally surrounds a needle operably coupled to the device to an administering position, in which the needle projects beyond said needle safety sleeve, said needle safety sleeve being releaseably blockable against displacement.