Antimicrobial wipes

• US 6,258,368 B1
• Filed: 06/04/1997
• Issued: 07/10/2001
• Est. Priority Date: 06/04/1997
• Status: Expired due to Fees

• Current Assignee: The Procter & Gamble Company
• Original Assignee: The Procter & Gamble Company
• Inventors: Beerse, Peter William, Morgan, Jeffrey Michael, Evans, Marcus Wayne, Baier, Kathleen Grieshop, Bakken, Theresa Anne
• Primary Examiner(s): Dodson, Shelley A.
• Application Number:
  US08/868,717
• Time in Patent Office: 1,497 Days
• Field of Search: 424/401, 424/402, 424/404, 424/78.03, 424/405
• US Class Current: 424/404
• CPC Class Codes: A61K 8/0208 Tissues; Wipes; Patches
• CPC Class Codes: A61P 17/00 Drugs for dermatological disorders
• CPC Class Codes: A61P 17/10 Anti-acne agents
• CPC Class Codes: A61Q 17/005 Antimicrobial preparations
• CPC Class Codes: C11D 1/37 Mixtures of compounds all of which are anionic
• CPC Class Codes: C11D 17/049 Cleaning or scouring pads; Wipes
• CPC Class Codes: C11D 3/042 Acids
• CPC Class Codes: C11D 3/2034 aromatic
• CPC Class Codes: C11D 3/2075 Carboxylic acids-salts thereof
• CPC Class Codes: C11D 3/3769 (Co)polymerised monomers containing nitrogen, e.g. carbonamides, nitriles or amines
• CPC Class Codes: C11D 3/48 Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions

Abstract

The present invention relates to an antimicrobial wipe comprising a porous or absorbent sheet impregnated with an antimicrobial cleansing composition, wherein the antimicrobial cleansing composition comprises from about 0.001% to about 5.0%, by weight of the antimicrobial cleansing composition, of an antimicrobial active; from about 0.05% to about 10%, by weight of the antimicrobial cleansing composition, of an anionic surfactant; from about 0.1% to about 10%, by weight of the antimicrobial cleansing composition, of a proton donating agent; and from about 3% to about 99.85%, by weight of the antimicrobial cleansing composition, water; wherein the composition is adjusted to a pH of from about 3.0 to about 6.0. The invention also encompasses methods for cleansing skin, reducing the number of germs on the skin, and providing residual effectiveness versus Gram positive and Gram negative bacteria using these products.

Claims

1. An antimicrobial wipe comprising a porous or absorbent sheet impregnated with an antimicrobial cleansing composition, wherein the antimicrobial cleansing composition comprises:

a. from about 0.001% to about 5.0%, by weight of the antimicrobial cleansing composition, of an antimicrobial active;

b. from about 0.05% to about 10%, by weight of the antimicrobial cleansing composition, of an anionic surfactant;

c. from about 0.1% to about 10%, by weight of the antimicrobial cleansing composition, of a proton donating agent; and

d. from about 3% to about 99.85%, by weight of the antimicrobial cleansing composition, water;

wherein the antimicrobial cleansing composition is adjusted to a pH of from about 3.0 to about 6.0.

2. An antimicrobial wipe according to claim 1 wherein the antimicrobial active is selected from the group consisting of triclosan, triclocarban, piroctone olamine, PCMX, ZPT, natural essential oils and their key ingredients, and mixtures thereof.

3. An antimicrobial wipe according to claim 2 wherein the proton donating agent is an organic acid having a Buffering Capacity of greater than about 0.005.

4. An antimicrobial wipe according to claim 3 wherein the anionic surfactant is selected from the group consisting of sodium and ammonium alkyl sulfates and ether sulfates having chain lengths of predominantly 12 and 14 carbon atoms, olefin sulfates having chain lengths of predominantly 14 and 16 carbon atoms, and paraffin sulfonates having an average chain length of from 13 to 17 carbon atoms, and mixtures thereof.

5. An antimicrobial wipe according to claim 4 wherein the proton donating agent is selected from the group comprising adipic acid, tartaric acid, citric acid, maleic acid, malic acid, succinic acid, glycolic acid, glutaric acid, benzoic acid, malonic acid, salicylic acid, gluconic acid, polyacrylic acid, their salts, and mixtures thereof.

6. An antimicrobial wipe according to claim 5 wherein the ratio of the amount of non-anionic surfactants to the amount of anionic surfactant in the antibacterial cleansing composition is less than 1:

1.

7. An antimicrobial wipe according to claim 6 wherein the antimicrobial active is present at a level ranging from about 0.05% to about 2%, the anionic surfactant is present at a level of from about 0.1% to about 4%, and the proton donating agent is present at a level of from about 0.5% to about 8%, by weight of the antimicrobial cleansing composition.

8. An antimicrobial wipe according to claim 7 wherein the antimicrobial cleansing composition is adjusted to a pH of from about 3.5 to about 5.0.

9. An antimicrobial wipe according to claim 8 wherein the antimicrobial active is present at a level ranging from about 0.1% to about 1%, the anionic surfactant is present at a level of from about 0.2% to about 1%, and the proton donating agent is present at a level of from about 1% to about 4%, by weight of the antimicrobial cleansing composition.

10. An antimicrobial wipe according to claim 9 wherein the pH is adjusted to from about 3.5 to about 4.5.

11. An antimicrobial wipe according to claim 10 wherein the antimicrobial active is Triclosan.

12. An antimicrobial wipe according to claim 11 wherein the proton donating agent is selected from the group consisting of malic acid, malonic acid, citric acid, succinic acid and lactic acid.

13. An antimicrobial wipe according to claim 12 wherein the anionic surfactant is ammonium lauryl sulfate.

14. An antimicrobial wipe according to claim 1 wherein the antimicrobial cleansing composition further comprises a mildness enhancing agent.

15. An antimicrobial wipe according to claim 14 wherein the mildness enhancing agent is selected from the group consisting of from about 0.1% to about 1.0%, by weight of the antimicrobial cleansing composition, of a mildness enhancing polymer, from about 20% to about 70%, by weight of the anionic surfactant, of a mildness enhancing co-surfactant, and mixtures thereof.

16. An antimicrobial wipe according to claim 14 wherein the mildness enhancing agent is from about 0.1% to about 30%, by weight of the antimicrobial cleansing composition, of a lipophilic skin moisturizing agent.

17. An antimicrobial wipe according to claim 1 wherein the antimicrobial cleansing composition further comprises from about 0.1% to about 10%, by weight of the antimicrobial cleansing composition, of acidic surfactant.

18. An antimicrobial wipe according to claim 1 wherein the antimicrobial cleansing composition comprises from about 0.15% to about 2%, by weight of the antimicrobial cleansing composition, of salicylic acid proton donating agent.

19. A method for providing residual effectiveness against transient Gram negative bacteria, improved residual effectiveness against Gram positive bacteria and improved immediate reduction of germs on human skin comprising contacting the skin with the antimicrobial wipe of claim 1 to apply a safe and effective amount of the antimicrobial cleansing composition on the skin.

20. A method for providing residual effectiveness against transient Gram negative bacteria, improved residual effectiveness against Gram positive bacteria and improved immediate reduction of germs on human skin comprising contacting the skin with the antimicrobial wipe of claim 7 to apply a safe and effective amount of the antimicrobial cleansing composition on the skin.

21. A method for providing residual effectiveness against transient Gram negative bacteria, improved residual effectiveness against Gram positive bacteria and improved immediate reduction of germs on human skin comprising contacting the skin with the antimicrobial wipe of claim 13 to apply a safe and effective amount of the antimicrobial cleansing composition on the skin.

22. A method for providing residual effectiveness against transient Gram negative bacteria, improved residual effectiveness against Gram positive bacteria and improved immediate reduction of germs on human skin comprising contacting the skin with the antimicrobial wipe of claim 16 to apply a safe and effective amount of the antimicrobial cleansing composition on the skin.

23. A method for providing residual effectiveness against transient Gram negative bacteria, improved residual effectiveness against Gram positive bacteria and improved immediate reduction of germs on human skin comprising contacting the skin with the antimicrobial wipe of claim 17 to apply a safe and effective amount of the antimicrobial cleansing composition on the skin.

24. A method for providing residual effectiveness against transient Gram negative bacteria, improved residual effectiveness against Gram positive bacteria and improved immediate reduction of germs on human skin comprising contacting the skin with the antimicrobial wipe of claim 18 a safe and effective amount of the antimicrobial cleansing composition on the skin.

25. A method for treating acne comprising contacting the skin with the antimicrobial wipe of claim 1 to apply a safe and effective amount of the antimicrobial cleansing composition on the skin.

26. An antimicrobial wipe according to claim 1, wherein the antimicrobial cleansing composition comprises from about 0.1% to about 4%, by weight of the antimicrobial cleansing composition, of the anionic surfactant.

27. An antimicrobial wipe according to claim 1, wherein the antimicrobial cleansing composition comprises from about 0.2% to about 1%, by weight of the antimicrobial cleansing composition, of the anionic surfactant.

28. An antimicrobial wipe according to claim 1, wherein the ratio of the amount of non-anionic surfactant to the amount of anionic surfactant in the antibacterial cleansing composition is less than 1:

1.

29. An antimicrobial wipe according to claim 1, wherein the ratio of the amount of non-anionic surfactant to the amount of anionic surfactant in the antibacterial cleansing composition is less than 1:

2.

30. An antimicrobial wipe according to claim 1, wherein the ratio of the amount of non-anionic surfactant to the amount of anionic surfactant in the antibacterial cleansing composition is less than 1:

4.