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Method and apparatus for inactivation of biological contaminants using endogenous alloxazine or isoalloxazine photosensitizers

  • US 6,258,577 B1
  • Filed: 07/21/1998
  • Issued: 07/10/2001
  • Est. Priority Date: 07/21/1998
  • Status: Expired due to Term
First Claim
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1. A method for decontamination of a fluid, by inactivation of microorganisms therein, sufficiently effective such that said fluid can be administered to a patient, said fluid also containing a component selected from the group consisting of biologically active protein, blood, and blood constituents, without destroying the biological activity of such component, said method comprising:

  • (a) adding an effective, non-toxic amount of an endogenous alloxazine or isoalloxazine photosensitizer to said fluid;

    (b) exposing the fluid of step (a) to photoradiation sufficient to activate the endogenous photosensitizer;

    (c) allowing said activated endogenous photosensitizer to inactivate said microorganisms.

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