Techniques for treating anxiety disorders by brain stimulation and drug infusion
First Claim
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1. A method of using one or more drugs to therapeutically treat an anxiety disorder by means of an implantable pump and a catheter having a proximal end coupled to the pump and a discharge portion for infusing therapeutic dosages of the one or more drugs, the method comprising the steps of:
- surgically implanting the catheter so that the discharge portion lies in a brain parenchyma; and
, operating the pump to discharge a predetermined dosage of the one or more drugs through the discharge portion of the catheter into the infusion site, whereby an anxiety disorder is treated.
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Abstract
Techniques using one or more drugs and/or electrical stimulation for treating an anxiety disorder by means of an implantable signal generator and electrode and/or an implantable pump and catheter. A catheter is surgically implanted in the brain to infuse the drugs, and one or more electrodes may be surgically implanted in the brain to provide electrical stimulation.
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Citations
20 Claims
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1. A method of using one or more drugs to therapeutically treat an anxiety disorder by means of an implantable pump and a catheter having a proximal end coupled to the pump and a discharge portion for infusing therapeutic dosages of the one or more drugs, the method comprising the steps of:
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surgically implanting the catheter so that the discharge portion lies in a brain parenchyma; and
,operating the pump to discharge a predetermined dosage of the one or more drugs through the discharge portion of the catheter into the infusion site, whereby an anxiety disorder is treated. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
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17. A method of using one or more drugs to therapeutically treat an anxiety disorder by means of a static device capable of storing and releasing the one or more drugs when implanted in the central nervous system, the method comprising the steps of:
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surgically implanting the static device so that the one or more drugs may be released in the central nervous system;
providing an electrical signal generator and an implantable electrode having a proximal end and a stimulation portion, the proximal end of the electrode coupled to the signal generator;
surgically implanting the electrode so that the stimulation portion may stimulate a site in a central nervous system chosen to have anxiolytic properties;
operating the signal generator to stimulate the chosen site in the central nervous system; and
,treating an anxiety disorder with the drug that may be released into the central nervous system and stimulating the chosen site in the central nervous system. - View Dependent Claims (18, 19)
sensing physiological parameters of a heightened state of anxiety; and
wherein said step of operating the signal generator includes the step of operating the signal generator in response to the step of sensing physiological parameters, whereby the electrical signal produced by the signal generator is regulated in accordance with the physiological parameter detected.
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19. The method of claim 18 wherein the step of sensing physiological parameters includes the step of implanting a sensor capable of sensing physiological parameters.
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20. A method of using one or more drugs to therapeutically treat an anxiety disorder by means of an implantable pump and a catheter having a proximal end coupled to the pump and a discharge portion for infusing therapeutic dosages of the one or more drugs, the method comprising the steps of:
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surgically implanting the catheter so that the discharge portion lies in an intrathecal space of a spinal cord; and
,operating the pump to discharge a predetermined dosage of the one or more drugs through the discharge portion of the catheter into the infusion site, whereby an anxiety disorder is treated.
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Specification