Method and apparatus for treatment of cardiac electromechanical dissociation

• US 6,263,241 B1
• Filed: 04/30/1999
• Issued: 07/17/2001
• Est. Priority Date: 04/30/1999
• Status: Active Grant

• Current Assignee: Intermedics Incorporated
• Original Assignee: Intermedics Incorporated
• Inventors: Deno, D. Curtis, Rosborough, John P.
• Primary Examiner(s): Kamm, William E.
• Application Number:
  US09/303,380
• Time in Patent Office: 809 Days
• Field of Search: 607/4, 607/6, 607/17, 607/23, 607/24, 607/5
• US Class Current: 607/6
• CPC Class Codes: A61N 1/385 Devices for inducing an abnormal cardiac function, e.g. fibrillation
• CPC Class Codes: A61N 1/39622 Pacing therapy

Abstract

An apparatus and method for treating post-defibrillation electromechanical dissociation (“EMD”). A first embodiment comprises an implantable defibrillator, which may include cardioversion and pacemaker capabilities, which has the capability of detecting and treating post defibrillation EMD. The stimulator/defibrillator has one or more leads with electrodes. At least one electrode for defibrillation may be an endocardial or epicardial electrode or other suitable defibrillation electrode. A sense circuit senses the electrical condition of the heart of the patient. A hemodynamic sensor senses a parameter correlated to the state of blood flow. The cardiac stimulator/defibrillator detects ventricular tachyarrhythmia including fibrillation and terminates ventricular tachyarrhythmia. After termination of the ventricular tachyarrhythmia, the stimulator/defibrillator can detect the presence of electrical rhythm in the heart correlated, however, with inadequate blood flow to sustain life. Under such conditions, the device provides an output to stimulate the heart to overcome electromechanical dissociation and restore adequate blood flow. The device may also be an external therapy device, as part of, or in conjunction with an external defibrillator. The method for treating the heart to restore blood flow where electromechanical dissociation occurs after termination of a ventricular tachyarrhythmia or ventricular fibrillation comprises identifying electromechanical disassociation after termination of a ventricular tachyarrhythmia or a fibrillation and providing electrical therapy, the therapy comprising a series of packets of electrical pulses.

Claims

1. An implantable cardiac stimulator/defibrillator comprising

a hermetically sealed case;

at least one lead having an electrode thereon, said electrode being electrically connected to said stimulator/defibrillator;

an indifferent electrode electrically connected to said stimulator/defibrillator;

a power source in said case;

a control circuit connected to said power source;

a sensing circuit capable of sensing the electrical condition of the heart of a patient;

a hemodynamic sensor capable of sensing a parameter correlated to the state of blood flow;

a correlation circuit associated with said control circuit capable of correlating a presence of electrical rhythm in the heart with an absence of a selected level of said parameter after an episode of tachyarrythmia; and

an output circuit responsive to said correlation and control circuits, said output circuit producing an electrical therapy between said electrode and said indifferent electrode, said therapy comprised of a series of packets of electrical pulses,

said pulses being from about 20 microseconds in length and having a frequency of from 20 Hz to about 500 Hz and an amplitude of from about 20 V to about 80 V and

said packets being comprised of from 1 to 40 pulses and leading pulses in adjacent packets being separated from each other by intervals of from about 0.1 seconds to about 2 seconds, and

said series lasting at least 2 seconds.

2. The stimulator/defibrillator of claim 1 wherein said pulses are less than about 400 microseconds in length.

3. The stimulator/defibrillator of claim 1 wherein said pulses have a frequency of from about 50 Hz to about 100 Hz.

4. The stimulator/defibrillator of claim 1 wherein said pulses have an amplitude of from about 20 V to about 60 V.

5. The stimulator/defibrillator of claim 1 wherein said pulses are about 150 milliseconds to about 250 milliseconds in length.

6. The stimulator/defibrillator of claim 5 wherein said packets are about 200 milliseconds in length.

7. The stimulator/defibrillator of claim 1 wherein the leading pulses in said adjacent packets are separated from each other by intervals of about 0.5 seconds.

8. The stimulator/defibrillator of claim 1 wherein said packets are comprised of about 20 pulses or less.

9. The stimulator/defibrillator of claim 1 further comprising means for synchronizing said therapy to a selected feature of the electrical condition of the heart.

10. The stimulator/defibrillator of claim 1 wherein said hemodynamic sensor is an impedance sensor.

11. The stimulator/defibrillator of claim 1 wherein said hemodynamic sensor is a flow sensor.

12. The stimulator/defibrillator of claim 1 wherein said hemodynamic sensor is a pressure sensor.

13. The stimulator/defibrillator of claim 1 wherein said hemodynamic sensor is an accelerometer.

14. The stimulator/defibrillator of claim 1 wherein said hemodynamic sensor is an acoustic sensor.

15. The stimulator/defibrillator of claim 1 wherein the electrode is a defibrillation electrode.

16. The stimulator/defibrillator of claim 15 wherein the defibrillation electrode is an endocardial electrode.

17. The stimulator/defibrillator of claim 15, wherein the indifferent electrode is at least part of the case of the stimulator/defibrillator.

18. The stimulator/defibrillator of claim 15 wherein said indifferent electrode is a lead electrode.

19. The stimulator/defibrillator of claim 1 where commencement of delivery of said therapy is synchronized with said electrical condition of the heart.