Ischemia detector

• US 6,264,606 B1
• Filed: 09/22/1999
• Issued: 07/24/2001
• Est. Priority Date: 02/07/1997
• Status: Expired due to Term

• Current Assignee: Pacesetter AB (Abbott Laboratories)
• Original Assignee: Pacesetter AB (Abbott Laboratories)
• Inventors: Norén, Kjell, Ekwall, Christer
• Primary Examiner(s): NASSER, ROBERT L
• Application Number:
  US09/355,683
• Time in Patent Office: 671 Days
• Field of Search: 607/3, 607/5, 607/17, 607/19, 607/20, 600/529-538, 600/300, 600/301, 600/484
• US Class Current: 600/300
• CPC Class Codes: A61B 5/0205 Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
• CPC Class Codes: A61B 5/0816 Measuring devices for examining respiratory frequency measuring frequency of electric signals G01R23/00
• CPC Class Codes: A61B 5/1107 Measuring contraction of parts of the body, e.g. organ, muscle apparatus for measuring work or force in general G01L
• CPC Class Codes: A61N 1/36521 the parameter being derived from measurement of an electrical impedance

Abstract

An ischemia detector has a patient workload sensor and a patient breathing sensor which emits a signal representing sensed workload, and a patient breathing sensor which emits a signal representing sensed breathing activity of a patient. These signals are supplied to a detector unit which identifies a state of ischemia upon an occurrence of a predetermined relation between the sensed workload and the sensed breathing activity. This predetermined relation is a sensed low workload and a simultaneously sensed high breathing activity.

Claims

1. An ischemia detector comprising:

a workload sensor which emits a workload sensor signal representing a sensed workload of a patient;

a breathing sensor which emits a breathing sensor signal representing breathing activity of a patient;

a detector unit connected to said workload sensor and to said breathing sensor and supplied with said workload sensor signal and said breathing sensor signal, said detector unit identifying a state of ischemia upon an occurrence of a predetermined relation between the sensed workload and the sensed breathing activity, said predetermined relation being a sensed low workload and a simultaneously sensed high breathing activity.

2. An ischemia detector as claimed in claim 1 wherein said predetermined relation is a linear relation between the sensed workload and the sensed breathing is activity.

3. An ischemia detector as claimed in claim 1 wherein said detector unit identifies said state of ischemia when the sensed workload is below a predetermined workload threshold value and the simultaneously sensed breathing activity is above a predetermined breathing threshold value.

4. An ischemia detector as claimed in claim 1 further comprising an averaging unit connected between said workload sensor and said breathing sensor, said averaging unit averaging said workload sensor signal and said breathing sensor signal during a plurality of time periods of respective predetermined lengths, and supplying an averaged workload signal, as said sensed workload to said detector unit and an averaged breathing activity, as said sensed breathing activity to said detector unit.

5. An ischemia detector as claimed in claim 1 wherein said workload sensor comprises an activity sensor which senses body movements of a patient.

6. An ischemia detector as claimed in claim 1 wherein said workload sensor comprises a muscular sound sensor.

7. An ischemia detector as claimed in claim 1 wherein said workload sensor comprises a sensor which senses pressure waves and body fluid.

8. An ischemia detector as claimed in claim 1 wherein said workload sensor comprises a sensor which senses metabolic changes of a patient.

9. An ischemia detector as claimed in claim 8 wherein said workload sensor senses changes in oxygen consumption.

10. An ischemia detector as claimed in claim 8 wherein said workload sensor senses changes in nutrition.

11. An ischemia detector as claimed in claim 1 wherein said breathing sensor comprises a sensor which senses breathing sounds in a thorax of a patient.

12. An ischemia detector as claimed in claim 1 wherein said breathing sensor comprises a sensor which senses lung volume changes in a patient.

13. An ischemia detector as claimed in claim 1 wherein said breathing sensor comprises a sensor which measures an amplitude modulation of cardiac activity.

14. An ischemia detector as claimed in claim 1 further comprising a device for recording an IECG of a patient, said IECG exhibiting a base line offset, and wherein said breathing sensor comprises a sensor which identifies a magnitude of said base line offset as a representation of said breathing activity.

15. An ischemia detector as claimed in claim 14 wherein said breathing sensor measures said base line offset on a small DC bias voltage.

16. An ischemia detector as claimed in claim 15 further comprising means for applying said DC bias voltage during a fraction of a breathing cycle of a patient and at predetermined times within a cardiac cycle.

17. An ischemia detector as claimed in claim 1 further comprising an alerting unit which is activated in response to identification of said state of ischemia by said detector unit.

18. An ischemia detector as claimed in claim 1 wherein said breathing sensor comprises two electrodes disposed spaced from each other on an electrode lead, and measures an AC impedance between said two electrodes.

19. An ischemia detector as claimed in claim 1 further comprising a housing having a conductive portion, and wherein said breathing sensor comprises an electrode on an electrode lead and measures an AC impedance between said electrode and said conductive portion of said housing.

20. An implantable heart stimulator comprising:

an ischemia detector comprising;

a workload sensor which emits a workload sensor signal representing a sensed workload of a patient a breathing sensor which emits a breathing sensor signal representing breathing activity of a patient, a detector unit connected to said workload sensor and to said breathing sensor and supplied with said workload sensor signal and said breathing sensor signal, said detector unit identifying a state of ischemia upon an occurrence of a predetermined relation between the sensed workload and the sensed breathing activity, said predetermined relation being a sensed low workload and a simultaneously sensed high breathing activity;

a pulse generator which emits stimulation pulses for delivery to a patient at a stimulation rate; and

means for varying said stimulation rate dependent on identification of a state of ischemia by said ischemia detector.