Method for diagnosing the presence and extent of halitosis activity

• US 6,264,615 B1
• Filed: 01/19/2000
• Issued: 07/24/2001
• Est. Priority Date: 01/21/1999
• Status: Expired due to Fees

• Current Assignee: Diamond General Development Corporation
• Original Assignee: Diamond General Development Corporation
• Inventors: Musinski, Donald L., Diamond, Howard
• Primary Examiner(s): Nasser, Robert L.
• Application Number:
  US09/487,753
• Time in Patent Office: 552 Days
• Field of Search: 600/345-350, 600/530
• US Class Current: 600/530
• CPC Class Codes: A61B 5/14542 for measuring blood gases A61B5/14551 takes precedence
• CPC Class Codes: A61B 5/1473 invasive, e.g. introduced into the body by a catheter A61B5/1482 takes precedence

Abstract

A method and apparatus for diagnosing the presence and extent of halitosis activity are disclosed. A method includes assaying for the presence of sulfides on the surface of a subject'"'"'s tongue in order to determine the concentrations of sulfides in the fluids.

Claims

1. A method for diagnosing the presence and extent of halitosis activity on the surface of a subject'"'"'s tongue by measuring the concentration of sulfides thereon, said method comprising the steps of:

providing a dual electrode probe having a sulfide-responsive measuring electrode and a reference electrode;

providing a voltage indicator for generating a data readout reflective of the strength of the electrical potential between the sulfide-responsive measuring electrode and the reference electrode;

electrically connecting the sulfide-responsive measurement electrode and the reference electrode to the voltage indicator;

positioning the probe in contact with the surface of the subject'"'"'s tongue such that both electrodes are in electrical contact with the surface of the tongue and the fluid disposed thereon wherein the fluid bridges the electrodes to cause a potential between sulfide-responsive measurement electrode and the reference electrode, the magnitude of the potential corresponds to the concentration of sulfides in the fluid;

reading the data readout provided by the voltage indicator and indicative of the concentration of sulfides on the surface of the tongue; and

comparing the data readout with a predetermined standard to determine the extent of the halitosis.

2. A method for diagnosing the presence and extent of halitosis activity in the mouth of a subject by measuring the concentration of sulfides present on the surface of the subject'"'"'s tongue, said method comprising the steps of:

providing a sulfide-responsive probe comprising a housing having a tip configured to probe the surface of the tongue, a measuring electrode and a reference electrode operative to establish an electrical potential therebetween when the tip is contacted with a sulfide containing fluid, the electrical potential being proportional to the concentration of sulfides in the fluid.

3. A probe for diagnosing the presence and extent of halitosis in a subject'"'"'s mouth by measuring the concentration of sulfides on the surface of the subject'"'"'s tongue, said probe comprising:

a housing having a first end defining a tip configured to probe the surface of the tongue;

a sulfide-responsive, measuring electrode supported by said housing with a surface portion thereof disposed in said tip so as to establish fluid communication with the fluid when said tip is disposed on the tongue;

a reference electrode supported by said housing at a location which will not contact the fluid when the tip is disposed in the mouth, said reference electrode having a surface portion thereof disposed in a body of a salt;

a salt bridge material which is disposed so as to establish a conductive path between said body of salt and said measuring electrode when the tip is disposed in contact with the fluid on the surface of the tongue;

a first electrical lead in electrical communication with the measuring electrode;

a second electrical lead in electrical communication with the reference electrode;

said probe being operative, when immersed in the fluid, to generate an electrical potential between said measuring electrode and said reference electrode which is proportional to the concentration of sulfide in the fluid; and

an electrochemical analyzer for relating said electrical potential to the extent of halitosis.

4. A probe as in claim 3 further including a hydration layer disposed in contact with said salt bridge material.

5. A probe as in claim 4, wherein said hydration layer comprises a porous organic polymer having a salt disposed within said pores.

6. A probe as in claim 5, wherein said organic polymer comprises cellulose acetate.

7. A probe as in claim 3, wherein said body of salt has a major portion of the surface thereof which is covered by a moisture impervious coating and a minor portion thereof which is free of said coating.

8. A probe as in claim 7, wherein said body of salt is a body of potassium chloride.

9. A probe as in claim 3, wherein said salt bridge material comprises an organic matrix having particles of a salt disposed therein.

10. A probe as in claim 9, wherein said organic matrix comprises a polymer.

11. A probe as in claim 10, wherein said polymer comprises an epoxy polymer.

12. A probe as in claim 9, wherein said salt comprises potassium chloride.