Prosthetic gastroesophageal valve

• US 6,264,700 B1
• Filed: 08/27/1998
• Issued: 07/24/2001
• Est. Priority Date: 08/27/1998
• Status: Expired due to Term

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Endonetics, Inc. (Medtronic Plc)
• Inventors: Kilcoyne, John, Kelleher, Brian S.
• Primary Examiner(s): Willse, David H.
• Assistant Examiner(s): STEWART, ALVIN J
• Application Number:
  US09/140,935
• Time in Patent Office: 1,062 Days
• Field of Search: 623/12, 623/2, 623/23.64, 623/23.65, 623/23.67, 623/23.68, 623/23.7, 623/23.76, 623/23.74, 623/23.72, 604/4
• US Class Current: 623/23.68
• CPC Class Codes: A61F 2/04 Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts A61F2/18, A61F2/20 take precedence; devices, other than stent-grafts, providing patency to, or preventing collapsing of, tubular structures of the body other than stent-grafts, e.g. stents A61F2/82; instruments specially adapted for placement or removal of stents or stent-grafts A61F2/95
• CPC Class Codes: A61F 2/2412 with soft flexible valve members, e.g. tissue valves shaped like natural valves check valves with flexible valve members in general F16K15/14
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2002/044 Oesophagi or esophagi or gullets

Abstract

Disclosed is a prosthetic gastroesophageal valve assembly, for transesophageal implantation to treat gastroesophageal reflux disease. The valve assembly includes an anchor for attachment to the wall of the esophagus and a valve permanently or removably connected to the anchor. Related devices and methods are also disclosed.

Claims

1. A method of treating gastroesophageal reflux disease, comprising the steps of:

providing a prosthetic gastroesophageal valve having an anchor and a valve releasable attached to the anchor;

positioning the valve assembly at about the base of the esophagus;

contacting the anchor to the wall of the esophagus or cardia to permit cellular ingrowth through the wall of the anchor.

2. A method as in claim 1, further comprising the step of expanding a tubular support within the anchor, to press the anchor against the adjacent tissue.

3. A method as in claim 2, further comprising the step of removing the tubular support from the anchor following a cellular ingrowth period of time.

4. A method as in claim 1, further comprising the step of removing the valve from the anchor while leaving the anchor in place within the esophagus.

5. A method of attaching a prosthesis to the esophagus or cardia, comprising the steps of:

providing a prosthesis having at least one cellular ingrowth surface thereon;

preparing a surface of the wall of the esophagus or cardia for attachment to the cellular ingrowth surface by mechanically abrading tissue from the surface of the wall of the esophagus;

contacting the cellular ingrowth surface to the prepared surface, and

permitting cellular ingrowth from the prepared surface into the cellular ingrowth surface to attach the prosthesis to the prepared surface.

7. A method as in claim 5, wherein the prosthesis comprises a valve.

8. A method as in claim 7, wherein the valve is permanently attached to the cellular ingrowth surface.

9. A method as in claim 7, wherein the valve is removably attached to the cellular ingrowth surface.

10. A method as in claim 5, wherein the cellular ingrowth surface comprises a porous material.

11. A method as in claim 10, wherein the material comprises PTFE.

12. A method as in claim 5, wherein the contacting step fuirther comprises positioning an expandable support within the esophagus to press the cellular ingrowth surface against the wall of the esophagus.

13. A method as in claim 12, wherein the permitting step comprises leaving the support in position for at least a cellular ingrowth period.

14. A method as in claim 13, wherein the period is between about 1 and 45 days.

15. A method as in claim 5, wherein the prosthesis comprises a flexible, porous, tubular sleeve.

16. A method as in claim 5, wherein the preparing the surface step comprises injuring a portion of the surface of the cardia.

6. A method of attaching a prosthesis to the esophagus or cardia, comprising the steps of:

providing a prosthesis having at least one cellular ingrowth surface thereon;

preparing a surface of the wall of the esophagus or cardia for attachment to the cellular ingrowth surface by contacting a chemical to the surface of the wall of the esophagus;

contacting the cellular ingrowth surface to the prepared surface, and permitting cellular ingrowth from the prepared surface into the cellular ingrowth surface to attach the prosthesis to the prepared surface.