×

Ophthalmic composition containing a carbonic anhydrase inhibitor and xanthan gum

  • US 6,264,935 B1
  • Filed: 06/14/1999
  • Issued: 07/24/2001
  • Est. Priority Date: 10/17/1996
  • Status: Expired due to Fees
First Claim
Patent Images

1. An ophthalmic composition for the treatment of ocular hypertension and glaucoma in a subject in need thereof, comprising a hypotonic solution of 0.1 to 2% (w/w) of xanthan gum and 0.5 to 5% (w/w) of a topical carbonic anhydrase inhibitor of the structural formula:

  • an individual diastereomer, an individual enantiomer or mixture thereof, or an ophthalmologically acceptable salt thereof, wherein;

    A is carbon or nitrogen;

    Z is —

    NHR or —

    OR;

    R is C1-6alkyl, either straight or branched chain;

    R1 is (a) hydrogen, (b) C1-3alkyl, or (c) C1-4alkoxy-C1-4alkyl; and

    X is —

    SO2

    or —

    C(O)—

    .

View all claims
  • 1 Assignment
Timeline View
Assignment View
    ×
    ×