Electrically assisted transdermal method and apparatus for the treatment of erectile dysfunction
First Claim
1. A method for enhancing erectile function in a subject, said method comprising applying an electric pulse to the penis and substantially contemporaneously applying a vasoactive or androgenic composition thereto, said electric pulse having sufficient strength and duration for transdermally introducing an effective amount of the composition into the penis, thereby enhancing erectile function in the subject.
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Abstract
A non-invasive method is provided for treating erectile dysfunction using electroporation enhanced with delivery of a vasoactive or androgenic composition applied to the penis which affords an alternative treatment for patients afflicted with erectile dysfunction (ED). Sufficient electric pulses temporarily create new pathways in the penile skin thereby driving a composition, such as a vasoactive or androgenic medication, into the corporal cavernosum.
85 Citations
23 Claims
- 1. A method for enhancing erectile function in a subject, said method comprising applying an electric pulse to the penis and substantially contemporaneously applying a vasoactive or androgenic composition thereto, said electric pulse having sufficient strength and duration for transdermally introducing an effective amount of the composition into the penis, thereby enhancing erectile function in the subject.
- 12. A method for treating impotence in a subject comprising applying an electric pulse to the penis of the subject and substantially contemporaneously applying a vasoactive or androgenic composition thereto, said electric pulse having sufficient strength and duration for transdermally introducing an effective amount of the composition into the penis thereby enhancing erectile function in the subject.
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23. A method for delivering a composition into the penis of a subject comprising applying an electric pulse to the penis and substantially contemporaneously applying the composition to the penis, said electric pulse having sufficient strength and duration for transdermally introducing the composition into the penis in an amount greater than provided by passive diffusion of the composition into the penis when applied thereto.
Specification