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High throughput screening assay systems in microscale fluidic devices

  • US 6,267,858 B1
  • Filed: 06/24/1997
  • Issued: 07/31/2001
  • Est. Priority Date: 06/28/1996
  • Status: Expired due to Term
First Claim
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1. A microfluidic device, comprising:

  • a body having at least a first microscale channel disposed therein;

    at least a first reservoir in fluid communication with the first microscale channel, the first reservoir having no electrodes disposed therein;

    at least a second reservoir connected to the first reservoir by a second channel; and

    at least a first electrode place into contact with a fluid disposed in the second reservoir;

    wherein the second channel is configured to retard the movement of one or more degradable components between the electrode and the first microscale channel, the second channel comprising one or more of;

    a cross-sectional dimension that is smaller than a cross-sectional dimension of the first channel; and

    a cross-sectional dimension that is smaller than a cross-sectional dimension of the first channel.

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