Stents

• US 6,273,908 B1
• Filed: 10/24/1997
• Issued: 08/14/2001
• Est. Priority Date: 10/24/1997
• Status: Expired due to Fees

• Current Assignee: Robert Ndondo-Lay
• Original Assignee: Robert Ndondo-Lay
• Inventors: Ndondo-Lay, Robert
• Primary Examiner(s): SNOW, BRUCE EDWARD
• Application Number:
  US08/957,241
• Time in Patent Office: 1,390 Days
• Field of Search: 623/1, 623/12, 606/108, 606/192, 606/194-5
• US Class Current: 623/1.43
• CPC Class Codes: A61F 2/885 comprising a coil including a plurality of spiral or helical sections with alternate directions around a central axis
• CPC Class Codes: A61K 45/06 Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
• CPC Class Codes: A61L 2300/416 Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
• CPC Class Codes: A61L 2300/42 Anti-thrombotic agents, anticoagulants, anti-platelet agents
• CPC Class Codes: A61L 2300/45 Mixtures of two or more drugs, e.g. synergistic mixtures
• CPC Class Codes: A61L 31/16 Biologically active materials, e.g. therapeutic substances A61L31/047 takes precedence
• CPC Class Codes: A61P 9/14 Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Abstract

A stent having cavities has been developed that can be quickly and easily used in a wide variety of situations, that keeps vessels open with a minimum degree of recoil and shortening lengthwise, that is flexible and can be delivered to the most distal lesion, and that can continuously deliver anticoagulant or other biologically active agents for an extended period directly at the site of stent placement. The stent of the present invention includes at least one flexible, serpentine backbone, and a plurality of opposing, outwardly-projecting appendages on said backbone, wherein said stent has a substantially circular cross-section.

Claims

1. A stent comprising:

a) a flexible, serpentine backbone defining a longitudinal axis of a substantially tubular member; and

b) a plurality of cavities integral to an inner and an outer surface of said backbone, wherein said cavities on said inner surface of said stent contain a first biologically active agent, and said cavities on said outer surface of said stent contain a second biologically active agent, wherein said first biologically active agent is different from said second biologically active agent.

2. A stent according to claim 1, wherein said first biologically active agent is an anti-thrombus agent, and said second biologically active agent is an anti-restenosis drug.