Injection device with electronic presentation of set doses

• US 6,277,098 B1
• Filed: 12/08/1997
• Issued: 08/21/2001
• Est. Priority Date: 03/12/1996
• Status: Expired due to Term

• Current Assignee: Novo Nordisk A/S
• Original Assignee: Novo Nordisk A/S
• Inventors: Klitmose, Lars Peter, Hansen, Henrik Egesborg
• Primary Examiner(s): Seidel, Richard K.
• Assistant Examiner(s): RODRIGUEZ, CRIS LOIREN
• Application Number:
  US08/981,772
• Time in Patent Office: 1,352 Days
• Field of Search: 604/201, 604/207, 604/19, 604/500, 604/48, 604/65, 604/130, 604/131, 604/140, 604/150, 604/151, 604/187
• US Class Current: 604/207
• CPC Class Codes: A61M 2005/3125 specific display means, e.g. to indicate dose setting
• CPC Class Codes: A61M 2205/50 with microprocessors or computers
• CPC Class Codes: A61M 2205/581 by audible feedback
• CPC Class Codes: A61M 2205/582 by tactile feedback
• CPC Class Codes: A61M 2205/8206 battery-operated
• CPC Class Codes: A61M 5/24 Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic ampoules or carpules A61J1/06
• CPC Class Codes: A61M 5/31525 Dosing burettes, pipettes B01L3/02
• CPC Class Codes: A61M 5/31546 Electrically operated dose setting, e.g. input via touch screen or plus/minus buttons
• CPC Class Codes: A61M 5/31553 without axial movement of dose setting member
• CPC Class Codes: A61M 5/31568 Means keeping track of the total dose administered, e.g. since the cartridge was inserted
• CPC Class Codes: A61M 5/3202 Devices for protection of the needle before use, e.g. caps A61M5/50 takes precedence; for infusion spikes A61M5/1626; protectors for sharps A61B50/3001

Abstract

An injection device has signal generators (11, 12, 13, 14) which are connected to operative elements (8, 3, 5, 4) of the device and which give off signals which represents the operative condition of the device. The signals are sent to an electronic circuit which controls a presentation of the operational condition of the device and presents operational conditions, which are defined as not allowed, as error indications by switching off the display presenting the operational condition of the device. The number of signals from each generator is counted and a number of operations exceeding a pre-set number for the signal generator in question is interpreted as representing a not allowed operational condition.

Claims

1. An injection device comprising:

a plurality of operative elements for setting and injecting of set doses of medicine;

signal generators connected to at least two of said operative elements to generate output signals representing operating conditions of said at least two operative elements, wherein the operating conditions indicated by such output signals individually are not indicative of whether an error state exists; and

an electronic circuit coupled to said signal generators for receiving said output signals and for determining whether the combination of said output signals indicates an error state for said device.

2. A device according to claim 1, wherein said electronic circuit further comprises means for generating an error signal responsive to identifying an error state.

3. A device according to claim 2, wherein said electronic circuit comprises a storage device containing all combinations of input signals which correspond to non-error states of said device, and a device for comparing said output signals with said stored combinations on a relatively frequent basis to detect the presence of error states.

4. A device according to claim 3, wherein said electronic circuit includes a circuit for counting the number of signals sent from each signal generator, a circuit for comparing such numbers with stored values, and a circuit generating a signal when a number exceeds its corresponding stored value.

5. A device according to claim 1, wherein at least one of said signal generators includes an electric switch having on and off positions.

6. A device according to claim 5, wherein at least one of said signal generators is an active generator.

7. A device according to claim 1, wherein at least one of said signal generators is an active generator.

8. A device according to claim 1, wherein said device further includes a means for generating an external presentation of the operating condition of the device and for switching off such external presentation when an error condition is detected.

9. A device according to claim 8, further including a means for resetting the means for switching off such external presentation.

10. A device according to claim 1, wherein said operative elements include a dose-setting device and an injection button and wherein said device includes a signal generator associated with each of said dose-setting device and said injection button.

11. A device according to claim 10, wherein said device includes a housing and said operative elements further include a protective cap, which can selectively be mounted on said housing, and a cartridge holder which can selectively be disengaged from said housing for changing cartridges, and said device includes a signal generator for detecting whether said cap is mounted on said housing and a signal generator for detecting when said cartridge holder is disengaged from said housing.

12. An injection device comprising a housing, a dose-setting wheel rotatably supported by said housing for setting an injection dose, an injection button supported by said housing and moveable between a plurality of first positions, corresponding to selected doses, and a second position for injecting the selected dose, a first signal generator connected to said dose-setting wheel for generating a first output signal in response to rotation of said wheel, a second signal generator for generating a second output signal indicative of whether said injection button is in said second position or one of said first positions, and an electronic circuit coupled to said signal generators for receiving said output signals and for comparing said output signals with one another to determine whether the combination of said output signals indicate an error state for said device.

13. A device according to claim 12, further comprising a cartridge holder which can be selectively mounted on said housing for holding a cartridge containing a medicine, and a third signal generator for generating a third output signal indicative of whether said cartridge holder is mounted on said housing, wherein said electronic circuit receives said third output signal and determines whether the combination of said first, second, and third output signals indicates an error state.

14. A device according to claim 13, further comprising a cap selectively mountable on said housing for selectively covering the cartridge holder, and a fourth signal generator for generating a fourth output signal indicative of whether the cap is mounted on the housing, and wherein said electronic circuit receives said fourth output signal for determining whether said fourth output signal, in combination with said first, second, and third output signals, indicates an error state.

15. An injection device comprising a housing, a dose-setting wheel rotatably supported by said housing for setting an injection dose, an injection button supported by said housing and moveable between a plurality of first positions, corresponding to selected doses, and a second position for injecting the selected dose, a first signal generator connected to said dose-setting wheel for generating a first output signal in response to rotation of said wheel, a second signal generator for generating a second output signal indicative of whether said injection button is in said second position or one of said first positions, and an electronic circuit coupled to said signal generators for storing a number value for each generator representing the predetermined maximum desired use of said device, for receiving and counting the number of signals from each generator, and for generating a signal when the number of signals exceeds a corresponding stored value for said generator.

16. A device according to claim 15, further comprising a cartridge holder which can be selectively mounted on said housing for holding a cartridge containing a medicine, and a third signal generator for generating a third output signal indicative of whether said cartridge holder is mounted on said housing, wherein said electronic circuit receives and counts the number of said third output signals and generates a signal when such number exceeds a corresponding stored value for said third signal generator.

17. A device according to claim 16, further comprising a cap selectively mountable on said housing for selectively covering the cartridge holder, and a fourth signal generator for generating a fourth output signal indicative of whether the cap is mounted on the housing, and wherein said electronic circuit receives and counts the number of said fourth output signals and generates a signal when the number of said fourth output signals exceeds a corresponding stored value for said fourth signal generator.