Corn extract contraceptive
First Claim
1. A process for producing an antineoplastic substance comprising:
- extracting a Zea mays plant product in a first solvent to produce a solvent extract, wherein said Zea mays plant product is selected from the group consisting of corn kernel, corn cob, animal bedding material made from corn cob, and mixtures thereof and wherein said first solvent comprises a solar solvent;
drying said solvent extract to produce an extracted solid;
solubilizing said extracted solid in a second solvent;
purifying said solubilized extract in a chromatographic process;
collecting an active fraction from said chromatographic process said active fraction being the antineoplastic substance and having antineoplastic activity.
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Accused Products
Abstract
Novel compositions extracted from corn products provide contraceptive and anti-neoplastic activities. Using novel extraction procedures, compositions may be isolated from corn products. For example, a Zea mays plant product is extracted in a first solvent to produce a solvent extract, the solvent extract is dried to produce an extracted solid, the extracted solid is solubilized in a second solvent, the solubilized extract is purified in a chromatographic process, and an active fraction is collected from the chromatographic process. Compositions may be applied to animal bedding or food, and are adaptable to any suitable method of administration. The contraceptive activity of these compositions is effective for both males and females.
51 Citations
27 Claims
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1. A process for producing an antineoplastic substance comprising:
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extracting a Zea mays plant product in a first solvent to produce a solvent extract, wherein said Zea mays plant product is selected from the group consisting of corn kernel, corn cob, animal bedding material made from corn cob, and mixtures thereof and wherein said first solvent comprises a solar solvent;
drying said solvent extract to produce an extracted solid;
solubilizing said extracted solid in a second solvent;
purifying said solubilized extract in a chromatographic process;
collecting an active fraction from said chromatographic process said active fraction being the antineoplastic substance and having antineoplastic activity. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24)
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25. An antineoplastic substance produced by a process comprising the steps of
extracting a Zea mays plant product in a first solvent to produce a solvent extract, wherein said Zea mays plant product is selected from the group consisting of corn kernel, corn cobs animal bedding material made from corn cob, and mixtures thereof, and wherein said first solvent comprises a solvent selected from the group consisting of alcohols, ethers, ketones, water and mixtures thereof; -
drying said solvent extract to produce an extracted solid;
solubilizing said extracted solid in a second solvent;
purifying said solubilized extract in a chromatographic process;
collecting an active fraction from said chromatographic process, said active fraction being the antineoplastic substance and having antineoplastic activity. - View Dependent Claims (26, 27)
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Specification