Medicating bandage and controllable permeable membrane

• US 6,283,938 B1
• Filed: 05/04/1999
• Issued: 09/04/2001
• Est. Priority Date: 05/04/1999
• Status: Expired due to Fees

• Current Assignee: Daniel E. Mcconnell
• Original Assignee: Daniel E. Mcconnell
• Inventors: McConnell, Daniel E.
• Primary Examiner(s): MENDEZ, MANUEL A
• Application Number:
  US09/304,873
• Time in Patent Office: 854 Days
• Field of Search: 604/65-67, 604/361, 604/318, 600/300, 602/41, 602/42, 602/43, 602/44, 602/45, 602/46, 602/47, 602/48, 602/49, 128/DIG.12, 128/13
• US Class Current: 604/66
• CPC Class Codes: A61K 9/0009 involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis microelectromechanical systems A61K9/0097
• CPC Class Codes: A61K 9/70 Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug hollow drug-filled fibres A61K9/0092

Abstract

A medicating bandage in which a controllable permeable membrane is interposed between a medication contained in a bandage pad and the skin of a patient undergoing medication. Passage of the medication through the membrane and into contact with the patient is metered by controlling the permeability of the membrane, preferably under the control of a biosensor and a microcontroller. The combination of a sensor and a controllable permeable membrane has usefulness apart from the bandage pad and medication.

Claims

1. A bandage comprising:

a pad having a body contacting surface;

a biosensor contained in said pad to provide a signal indicative of a biological state of a contacted body;

a biologically active medication contained in said pad; and

a controllable permeable membrane interposed between said medication and said body contacting surface and connected to said biosensor to respond to said signal by metering release of said medication at said body contacting surface.

2. A bandage according to claim 1 wherein said biosensor provides a signal indicative of at least one of (a) the temperature characteristics of a contacted body surface and (b) the surface electrical conductivity of a contacted body surface and (c) the surface chemistry characteristics of a contacted body surface and (d) the contact pressure exerted between said pad and a contacted body surface and (e) the coloration characteristics of a contacted body surface.

3. A bandage according to claim 1 wherein said biosensor provides a signal indicative of the temperature characteristics of a contacted body surface.

4. A bandage according to claim 1 wherein said biosensor provides a signal indicative of the surface electrical conductivity characteristics of a contacted body surface.

5. A bandage according to claim 1 wherein said biosensor provides a signal indicative of the surface chemistry characteristics of a contacted body surface.

6. A bandage according to claim 1 wherein said biosensor provides a signal indicative of the contact pressure characteristics between said pad and a contacted body surface.

7. A bandage according to claim 1 wherein said biosensor provides a signal indicative of the coloration characteristics of a contacted body surface.

8. A bandage according to claim 1 wherein said biosensor provides a signal indicative of at least two of the temperature, surface electrical conductivity, surface chemistry, and coloration characteristics of a contacted body surface.

9. A bandage comprising:

a pad having a body contacting surface;

a biosensor contained in said pad to provide an electrical signal indicative of a biological state of a contacted body;

a biologically active medication contained in said pad;

an electrically controllable permeable membrane interposed between said medication and said body contacting surface to meter release of said medication at said body contacting surface; and

a control circuit contained in said pad and operatively interconnecting said biosensor and said membrane for translating said signal into a control signal provided to said membrane to control metering of medication release.

10. A bandage according to claim 9 wherein said control circuit comprises a microcontroller contained within said pad and a memory device connected to said microcontroller and storing a digital program executable by said microcontroller to vary said control signal in a predetermined manner in response to said signal.

11. A bandage according to claim 10 wherein said microcontroller and said memory device cooperate to meter medication release as a linear function of said signal between predetermined minima and maxima.

12. A bandage according to claim 10 wherein said microcontroller and said memory device cooperate to meter medication release as a nonlinear function of said signal between predetermined minima and maxima.

13. A bandage according to claim 10 wherein said microcontroller and said memory device cooperate to meter medication release as a function of said signal and of the passage of time.

14. A bandage according to claim 9 wherein said electrically controllable permeable membrane cooperates with said medication to induce flow of said medication to said contact surface.

15. A bandage according to claim 9 wherein said electrically controllable permeable membrane cooperates with said medication to limit flow of said medication to said contact surface.

16. A bandage according to claim 9 wherein said electrically controllable permeable membrane comprises an electrically conductive web.

17. A bandage according to claim 16 wherein said web comprises knitted together electrically conductive strands.

18. A bandage according to claim 16 wherein said web comprises woven together electrically conductive strands.

19. A bandage according to claim 16 wherein said electrically controllable permeable membrane comprises a pair of electrically conductive webs spaced one from the other by a dielectric layer.

20. A bandage according to claim 19 wherein each of said webs comprises knitted together electrically conductive strands.

21. A bandage according to claim 19 wherein each of said webs comprises woven together electrically conductive strands.

22. A bandage according to claim 16 wherein said electrically controllable permeable membrane comprises an electrostrictive web.

23. A bandage according to claim 22 wherein said web comprises knitted together electrically conductive strands.

24. A bandage according to claim 22 wherein said web comprises woven together electrically conductive strands.

25. A bandage comprising:

a pad having a body contacting surface;

a biosensor contained in said pad to provide an electrical signal indicative of a biological state of a contacted body;

a biologically active medication contained in said pad;

an electrically controllable permeable membrane having an electrically conductive web interposed between said medication and said body contacting surface to meter release of said medication at said body contacting surface; and

a microcontroller and a memory device connected to form a control circuit contained in said pad and operatively interconnecting said biosensor and said web and translating said signal into a control signal provided to said membrane to control metering of medication release as a function of said signal.

26. A method comprising:

applying a bandage pad containing a medication and a biosensor to the skin surface of a patient;

sensing with the biosensor a biological state of the patient; and

metering the release of medication to the skin surface of the patient under the control of a microcontroller contained in the pad by controlling the passage of medication through a controllable permeable membrane interposed between the medication contained in the pad and the skin contacting surface of the pad and operatively connected to the microcontroller.

27. A method according to claim 26 wherein the step of controlling the passage of medication comprises generating at the biosensor an electrical signal indicative of the biological state of the patient, supplying the generated signal to the microcontroller, generating at the microcontroller a control signal which is a function of the electrical signal, and supplying the control signal to the controllable permeable membrane.

28. Apparatus comprising:

an electrically controllable permeable membrane which meters the passage of a material therethrough from a supply side to a delivery side and

a sensor responsive to conditions on the delivery side of the membrane and which generates an electrical signal indicative of a condition which can be affected by the material;

said sensor being connected to said membrane and said membrane being responsive to said signal for varying the metering of the material.

29. Apparatus according to claim 28 wherein said electrically controllable permeable membrane comprises an electrically conductive web.

30. Apparatus according to claim 29 wherein said web comprises knitted together electrically conductive strands.

31. Apparatus according to claim 29 wherein said web comprises woven together electrically conductive strands.

35. Apparatus according to claim 29 wherein said electrically controllable permeable membrane comprises an electrostrictive web.

36. Apparatus according to claim 35 wherein said web comprises knitted together electrically conductive strands.

37. Apparatus according to claim 35 wherein said web comprises woven together electrically conductive strands.

32. Apparatus according to claim 32 wherein said electrically controllable permeable membrane comprises a pair of electrically conductive webs spaced one from the other by a dielectric layer.

33. Apparatus according to claim 32 wherein each of said webs comprises knitted together electrically conductive strands.

34. Apparatus according to claim 32 wherein each of said webs comprises woven together electrically conductive strands.