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Apparatus and method for removing small molecules and ions from low volume biological samples

  • US 6,284,117 B1
  • Filed: 12/22/1999
  • Issued: 09/04/2001
  • Est. Priority Date: 12/22/1999
  • Status: Expired due to Term
First Claim
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1. An apparatus for lowering the ionic strength of a low volume solution used inthe electronic transport of nucleic acids, proteins, and/or cells comprising:

  • a tubular molecular weight cut-off membrane having a lumen, ion exchange resin, and a chamber surrounding and housing said membrane and resin wherein said membrane has an entrance and an exit port leading through said chamber, said membrane further embedded in and amongst said resin, and said chamber having entrance and exit ports for exchanging a flowable material into and out of said chamber.

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