Methods and apparatus for improved administration of fentanyl and sufentanil
First Claim
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1. A method of controlling the rate of analgesic delivery to a systemic circulation of a human body comprising:
- applying a transdermal analgesic delivery system to the skin of said human body for delivery of an analgesic to said systemic circulation of said human body;
applying a temperature modification apparatus capable of generating controlled heat proximate said transdermal analgesic delivery system by exposing an oxygen activated exothermic medium within the apparatus to oxygen and varying the amount of oxygen to which the exothermic medium is exposed to vary a rate of reaction of the exothermic medium; and
heating said skin of said human body proximate said transdermal analgesic delivery system with said temperature modification apparatus to achieve an increased rate of delivery of analgesic to said systemic circulation of said human body.
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Abstract
Methods and apparatus for improving administration of analgesics through the use of heat. The present invention relates to the use of heat in conjunction with specially designed transdermal analgesic delivery systems and conventional commercial transdermal analgesic delivery systems to alter, mainly increase, the analgesic release rate from the transdermal analgesic delivery systems or the depot sites to accommodate certain clinical needs.
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Citations
12 Claims
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1. A method of controlling the rate of analgesic delivery to a systemic circulation of a human body comprising:
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applying a transdermal analgesic delivery system to the skin of said human body for delivery of an analgesic to said systemic circulation of said human body;
applying a temperature modification apparatus capable of generating controlled heat proximate said transdermal analgesic delivery system by exposing an oxygen activated exothermic medium within the apparatus to oxygen and varying the amount of oxygen to which the exothermic medium is exposed to vary a rate of reaction of the exothermic medium; and
heating said skin of said human body proximate said transdermal analgesic delivery system with said temperature modification apparatus to achieve an increased rate of delivery of analgesic to said systemic circulation of said human body. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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Specification