Drug coating with topcoat
First Claim
1. A method of coating an implantable stent prosthesis having at least a portion which is implantable into the body of a patient, wherein at least a part of the stent portion is covered with a coating for release of at least one biologically active material;
- the method comprising;
(a) applying an undercoat comprising a polymeric material and the biologically active material to the stent portion wherein the undercoat has a surface; and
(b) applying a discontinuous topcoat which covers less than the entire surface of the undercoat, said topcoat comprising a polymeric material, substantially free of pores and pore-forming materials.
2 Assignments
0 Petitions
Accused Products
Abstract
A coating and method for a coating an implantable device or prostheses are disclosed. The coating includes an undercoat of polymeric material containing an amount of biologically active material, particularly heparin, dispersed therein. The coating further includes a topcoat which covers less than the entire surface of the undercoat and wherein the topcoat comprises a polymeric material substantially free of pores and porosigens. The polymeric material of the topcoat can be a biostable, biocompatible material which provides long term non-thrombogenicity to the device portion during and after release of the biologically active material.
428 Citations
12 Claims
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1. A method of coating an implantable stent prosthesis having at least a portion which is implantable into the body of a patient, wherein at least a part of the stent portion is covered with a coating for release of at least one biologically active material;
- the method comprising;
(a) applying an undercoat comprising a polymeric material and the biologically active material to the stent portion wherein the undercoat has a surface; and
(b) applying a discontinuous topcoat which covers less than the entire surface of the undercoat, said topcoat comprising a polymeric material, substantially free of pores and pore-forming materials. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
- the method comprising;
Specification