Implantable stimulation device and method for determining atrial autocapture using programmable AV delay

• US 6,285,908 B1
• Filed: 08/23/1999
• Issued: 09/04/2001
• Est. Priority Date: 05/14/1996
• Status: Expired due to Term

• Current Assignee: Pacesetter Incorporated (Abbott Laboratories)
• Original Assignee: Pacesetter Incorporated (Abbott Laboratories)
• Inventors: Levine, Paul A., Mann, Brian M., Endaya, Melinda
• Primary Examiner(s): Schaetzle, Kennedy
• Application Number:
  US09/379,043
• Time in Patent Office: 743 Days
• Field of Search: 607/28, 607/14, 607/27, 607/9
• US Class Current: 607/28
• CPC Class Codes: A61N 1/3682 with a variable atrioventricular delay
• CPC Class Codes: A61N 1/3712 Auto-capture, i.e. automatic adjustment of the stimulation threshold
• CPC Class Codes: A61N 1/3714 Atrial capture

Abstract

A pacemaker programmer and diagnostic system retrieves information stored within a pacemaker and analyzes the retrieved data in real time. The stored information can be retrieved by means of a telemetry communication link. The pacemaker automatically lengthens a post-ventricular atrial refractory period (PVARP). The pacemaker determines atrial capture threshold by generating atrial stimulation pulses while maintaining the ventricular stimulation pulse amplitude at a level known to ensure ventricular capture, and by detecting loss of atrial capture. In response to the loss of atrial capture, a processor automatically shortens the AV delay in a subsequent cardiac cycle, to reduce the possibility of a retrograde P-wave initiating a pacemaker-mediated tachycardia (PMT). Also in response to the loss of atrial capture, the pacemaker records the atrial capture threshold, restores the PVARP to its pre-test value, and sets the atrial stimulation pulse amplitude to a value above the atrial capture threshold.

Claims

1. A method of determining an atrial capture threshold in a stimulation device having a programmable AV delay, the method comprising:

generating an atrial stimulation pulse;

detecting loss of capture of the atrial stimulation pulse; and

in response to the loss of capture, automatically shortening the AV delay in a subsequent cardiac cycle to reduce the possibility of a retrograde P-wave initiating a tachycardia event.

2. The method, as recited in claim 1, further including retrieving historical data from the stimulation device to estimate an atrial stimulation pulse amplitude at which loss of capture would occur.

3. The method, as recited in claim 2, wherein generating the atrial stimulation pulse includes determining an initial atrial stimulation pulse amplitude based on the atrial stimulation pulse amplitude estimated from the historical data.

4. The method, as recited in claim 3, wherein generating the atrial stimulation pulse includes setting the amplitude of the initial atrial stimulation pulse to a predetermined level above the estimated atrial stimulation pulse amplitude.

5. The method, as recited in claim 4, wherein setting the amplitude of the initial atrial stimulation pulse includes increasing the amplitude of the initial atrial stimulation pulse a step immediately above the estimated atrial stimulation pulse amplitude.

6. The method, as recited in claim 1, further including maintaining a ventricular stimulation pulse amplitude at a level known to ensure ventricular capture.

7. The method, as recited in claim 1, wherein detecting loss of capture includes adjusting an amplitude of the atrial stimulation pulse until loss of capture occurs.

8. The method, as recited in claim 1, further including lengthening a post-ventricular atrial refractory period (PVARP) of the stimulation device to reduce the possibility of premature and retrograde P-waves being detected as true cardiac contractions.

9. The method, as recited in claim 8, wherein lengthening the PVARP includes lengthening the PVARP before detecting loss of capture.

10. The method, as recited in claim 8, wherein lengthening the PVARP includes increasing the PVARP in incremental steps.

11. The method, as recited in claim 8, wherein lengthening the PVARP includes increasing the PVARP to a programmed value.

12. The method, as recited in claim 1, wherein if loss of capture is not detected, decreasing an atrial stimulation pulse amplitude until loss of capture is detected.

13. The method, as recited in claim 12, wherein if loss of capture is detected, setting a capture threshold as the atrial stimulation pulse amplitude at which loss of capture occurs.

14. The method, as recited in claim 13, further including setting the atrial stimulation pulse amplitude to a value above the capture threshold.

15. The method, as recited in claim 9, further including, in response to loss of capture:

restoring the PVARP to a base value; and

restoring the atrial stimulation pulse to a base amplitude.

16. A stimulation device for determining an atrial capture threshold and having a programmable AV delay, comprising:

a pulse generator for generating an atrial stimulation pulse;

detection circuitry coupled to the pulse generator for detecting loss of capture of the atrial stimulation pulse; and

a processor, coupled to the pulse generator and the detection circuitry, for automatically shortening the AV delay in a subsequent cardiac cycle, in response to the loss of capture, to reduce the possibility of a retrograde P-wave initiating a tachycardia event.

17. The stimulation device, as recited in claim 16, further including memory for storing historical data;

wherein the processor retrieves the historical data; and

wherein based on the historical data, the processor estimates an atrial stimulation pulse amplitude at which loss of capture would occur, and sets the amplitude of the initial atrial stimulation pulse to a predetermined level above the estimated atrial stimulation pulse amplitude.

18. The stimulation device, as recited in claim 16, wherein the detecting circuitry detects loss of capture by adjusting an amplitude of the atrial stimulation pulse until loss of capture occurs.

19. The stimulation device, as recited in claim 16, further including a programmable post-ventricular refractory period (PVARP);

and

wherein the processor includes timing circuitry for lengthening the PVARP before detecting loss of capture, to reduce the possibility of premature and retrograde P-waves being detected as true cardiac contractions.

20. The stimulation device, as recited in claim 19, wherein if the detection circuitry does not detect loss of capture, the timing circuitry decreases an atrial stimulation pulse amplitude until loss of capture is detected.

21. The stimulation device, as recited in claim 19, wherein the processor includes control circuitry;

wherein if loss of capture is detected, the control circuitry sets a capture threshold as the atrial stimulation pulse amplitude at which loss of capture occurs; and

wherein the control circuitry sets the atrial stimulation pulse amplitude to a value above the capture threshold.

22. The stimulation device, as recited in claim 19, wherein the timing circuitry restores the PVARP to a base value in response to loss of capture.

23. The stimulation device, as recited in claim 16, wherein the stimulation device is a dual-chamber implantable cardiac pacing device.

24. A stimulation device for determining an atrial capture threshold and having a programmable AV delay, comprising:

pulse generator for generating an atrial stimulation pulse;

detection means coupled to the pulse generator, detecting loss of capture of the atrial stimulation pulse; and

processing means, coupled to the pulse generator and the detection means, for automatically shortening the AV delay in a subsequent cardiac cycle, in response to the loss of capture, to reduce the possibility of a retrograde P-wave initiating a pacemaker-mediated tachycardia.

25. The stimulation device, as recited in claim 24, wherein the processing means includes a control circuitry that sets the atrial stimulation pulse amplitude to a value above the capture threshold.

26. The stimulation device, as recited in claim 24, further including a programmable post-ventricular refractory period (PVARP);

and

wherein the processing means includes timing means for lengthening the PVARP before the detection of loss of capture, to reduce the possibility of premature and retrograde P-waves being detected as true cardiac contractions.