Guidewire with a variable stiffness distal portion

• US 6,287,292 B1
• Filed: 04/06/1999
• Issued: 09/11/2001
• Est. Priority Date: 04/18/1996
• Status: Expired due to Term

• Current Assignee: Advanced Cardiovascular Systems Incorporated
• Original Assignee: Advanced Cardiovascular Systems Incorporated
• Inventors: Fariabi, Sepehr
• Primary Examiner(s): Nguyen, Anhtuan T.
• Assistant Examiner(s): Thompson, Michael M
• Application Number:
  US09/287,703
• Time in Patent Office: 889 Days
• Field of Search: 128/898, 604/500, 604/28, 604/526, 604/528, 604/530-2, 604/523, 600/433, 600/434
• US Class Current: 604/531
• CPC Class Codes: A61M 2025/09141 made of shape memory alloys which take a particular shape at a certain temperature
• CPC Class Codes: A61M 2025/09175 having specific characteristics at the distal tip
• CPC Class Codes: A61M 25/0158 with magnetic or electrical means, e.g. by using piezo materials, electroactive polymers, magnetic materials or by heating of shape memory materials
• CPC Class Codes: A61M 25/09 Guide wires

Abstract

A guidewire having a core section formed of a NiTi alloy which is in an austenite phase when being manufactured but which is converted to the martensite phase at operating (body) temperature (37° C.) and can be transformed to an austenite phase by heating to a temperature above body temperature but below 50° C. When in the austenite phase, the core section is at a high strength level which ensures the tracking of a catheter over the guidewire within a patient'"'"'s body lumen. In one preferred embodiment the core section is heated by electrical resistance or inductance.

Claims

1. A method of performing an intraluminal procedure within a patient'"'"'s body lumen comprising:

a) providing a guidewire which has a distal core section and an intermediate core section, the intermediate core section having proximal and distal ends and being formed of a NiTi alloy with a substantial level of martensite phase at body temperature and with a final austenite transformation temperature above body temperature but below 50°

C. and the distal core section which has proximal and distal ends and which is secured by its proximal end to the distal end of the intermediate core section and which is electrically isolated from the intermediate core section;

b) positioning the guidewire at a desirable location within the patient'"'"'s body lumen;

c) heating the intermediate core section to a temperature above body temperature to convert at least part of the martensite phase of the intermediate core section to the austenite phase; and

d) advancing a catheter over the intermediate core section of the guidewire while the intermediate core section is predominantly in the austenite phase to a desired location within the patient'"'"'s body lumen.

2. The method of claim 1 wherein at least 50% of the martensite phase in the intermediate core section is converted to the austenite phase when the intermediate core section is heated within the body lumen.