Lung reduction device, system, and method

• US 6,293,951 B1
• Filed: 08/24/1999
• Issued: 09/25/2001
• Est. Priority Date: 08/24/1999
• Status: Expired due to Term

• Current Assignee: Gyrus ACMI, Inc. (Olympus Corporation)
• Original Assignee: Spiration, Inc. (Olympus Corporation)
• Inventors: Alferness, Clifton A., Lin, Richard Y., Jaeger, Wilfred E.
• Primary Examiner(s): Mancene, Gene
• Assistant Examiner(s): Robert, Eduardo C.
• Application Number:
  US09/379,972
• Time in Patent Office: 763 Days
• Field of Search: 604/246, 604/247, 604/249, 604/256, 604/48, 606/108, 606/200, 606/213, 606/217, 623/1.24, 623/1.26, 623/23.68, 623/1.25, 623/23.7
• US Class Current: 606/108
• CPC Class Codes: A61B 17/12104 in an air passage
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61F 2/02 Prostheses implantable into the body closure means for urethra or rectum or for artificial body openings therefor A61F2/0004
• CPC Class Codes: A61F 2/04 Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts A61F2/18, A61F2/20 take precedence; devices, other than stent-grafts, providing patency to, or preventing collapsing of, tubular structures of the body other than stent-grafts, e.g. stents A61F2/82; instruments specially adapted for placement or removal of stents or stent-grafts A61F2/95
• CPC Class Codes: A61F 2/24 Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
• CPC Class Codes: A61F 2/2476 Valves implantable in the body not otherwise provided for
• CPC Class Codes: A61F 2002/043 Bronchi

Abstract

A device, system, and method provides for lung size reduction by permanently collapsing at least a portion of a lung. The lung portion may be collapsed by obstructing the air passageway which communicates the lung portion to be collapsed. The air passageway may be obstructed by an obstructing member which precludes airflow in either direction or with a one-way valve which permits air to be exhaled from the lung portion while precluding air from being inhaled into the lung portion. In addition, a vacuum may be pulled within the lung portion to be collapsed for collapsing the lung portion and while the lung portion is collapsed the obstructing member may be placed in the air passageway to maintain the lung portion in a permanently collapsed state.

Claims

1. A bronchial sub-branch obstruction device for reducing the size of a lung comprising an obstructing member dimensioned for insertion into a bronchial sub-branch communicating with a portion of the lung to be reduced in size, the obstructing member having an outer dimension which is so dimensioned as to make continuous contact with an inner dimension of the bronchial sub-branch to seal the bronchial sub-branch upon placement in the bronchial sub-branch, to preclude normal function of the lung portion, and to collapse the portion of the lung for reducing the size of the lung, wherein the obstructing member is a one-way valve to permit exhaled air to flow from the lung portion while precluding inhaled air from flowing into the lung portion.

2. The device of claim 1 wherein the obstructing member is formed of resilient material so as to be collapsible for initial insertion into the bronchial sub-branch in a collapsed condition and releasable to define the outer dimension upon placement in the bronchial sub-branch.

3. The device of claim 1 wherein the obstructing member includes a generally circular base having an outer periphery and a circumferential generally cylindrical sidewall extending from the outer periphery of the base, the generally cylindrical sidewall having an outer surface defining the outer dimension.

4. The device of claim 3 wherein the obstructing member is formed of resilient material.

5. The device of claim 4 wherein the obstructing member is formed of silicone rubber.

6. The device of claim 4 wherein the obstructing member sidewall includes an inner generally cylindrical surface and wherein the obstructing member includes a resilient reinforcement rib in contact with the inner generally cylindrical surface.

7. The device of claim 6 wherein the reinforcement rib has a serpentine configuration.

8. The device of claim 6 wherein the base, the generally cylindrical sidewall, and the resilient reinforcement rib of the obstructing member are all collapsible and wherein the resilient reinforcement rib forces the cylindrical sidewall radially outwardly when the obstructing member is positioned in the air passageway to form the generally circular base and circumferential generally cylindrical sidewall.

9. A bronchial sub-branch obstruction system for reducing the size of a lung comprising:

a conduit configured to be passed down a trachea, into a bronchus communicating with the trachea, and into a bronchial sub-branch communicating the bronchus with a lung portion to be reduced in size; and

an obstructing member so dimensioned as to be guidable through the conduit and placed in the bronchial sub-branch to seal the bronchial sub-branch, to preclude normal function of the lung portion, and to collapse the lung portion, wherein the obstructing member is a one-way valve to permit exhaled air to flow from the lung portion while precluding inhaled air from flowing into the lung portion.

10. The system of claim 9 wherein the obstructing member is formed of resilient material so as to be collapsible for initial insertion through the conduit into the bronchial sub-branch in a collapsed condition and releasably expandable so as to be dimensioned to seal the bronchial sub-branch.

11. The system of claim 9 wherein the obstructing member includes a generally circular base having an outer periphery and a circumferential generally cylindrical sidewall extending from the outer periphery of the base, the generally cylindrical sidewall having an outer surface for continuous engagement with the bronchial sub-branch.

12. The system of claim 11 wherein the obstructing member is formed of resilient material.

13. The system of claim 12 wherein the obstructing member is formed of silicone rubber.

14. The system of claim 12 wherein the obstructing member sidewall includes an inner generally cylindrical surface and wherein the obstructing member includes a resilient reinforcement rib in contact with the inner generally cylindrical surface.

15. The system of claim 14 wherein the reinforcement rib has a serpentine configuration.

16. The system of claim 14 wherein the base, the generally cylindrical sidewall, and the resilient reinforcement rib of the obstructing member are all collapsible and wherein the resilient reinforcement rib forces the cylindrical sidewall radially outwardly when the obstructing member is positioned in the bronchial sub-branch to form the generally circular base and circumferential cylindrical sidewall.

17. A system for reducing the size of a lung comprising:

a conduit configured to be passed down a trachea, into a bronchus communicating with the trachea, and into an air passageway communicating the bronchus with a lung portion to be reduced in size;

an obstructing member configured to be guided through the conduit into the air passageway for placement in the air passageway and sealing the air passageway for collapsing the lung portion; and

a vacuum source for pulling a vacuum in the lung portion prior to placement of the obstructing member.

18. The system of claim 17 wherein the vacuum source is configured for being coupled to the conduit for pulling the vacuum through the conduit.

19. The system of claim 17 wherein the conduit has an outer dimension smaller than an inner dimension of the passageway, and wherein the system further includes sealing means for sealing between the conduit outer dimension and the air passageway inner dimension.

20. The system of claim 19 wherein the sealing means comprises an inflatable member.

21. The system of claim 20 wherein the conduit includes a first channel for guiding the obstructing member and a second channel for inflating the inflatable member.

22. A bronchial sub-branch obstruction device for reducing the size of a lung comprising an obstructing member dimensioned for insertion into a bronchial sub-branch communicating with a portion of the lung to be reduced in size, the obstructing member having an outer dimension which is so dimensioned as to make continuous contact with an inner dimension of the bronchial sub-branch to seal the bronchial sub-branch upon placement in the bronchial sub-branch to preclude air from being exhaled from the lung portion and inhaled into the lung portion for collapsing the portion of the lung and reducing the size of the lung, wherein the obstructing member is a one-way valve to permit exhaled air to flow from the lung portion while precluding inhaled air from flowing into the lung portion.

23. A bronchial sub-branch obstruction system for reducing the size of a lung comprising:

a conduit configured to be passed down a trachea, into a bronchus communicating with the trachea, and into a bronchial sub-branch communicating the bronchus with a lung portion to be reduced in size; and

an obstructing member so dimensioned as to be guidable through the conduit and placed in the bronchial sub-branch to seal the bronchial sub-branch to preclude air from being exhaled from the lung portion and inhaled into the lung portion and to collapse the lung portion, wherein the obstructing member is a one-way valve to permit exhaled air to flow from the lung portion while precluding inhaled air from flowing into the lung portion.