Methods involving changing the constitutive and stimulated secretions of the local reproductive system of women
First Claim
1. A method of affecting the amount of or properties of the cervical and vaginal mucosa comprising administering an effective amount of a composition comprising a compound selected from the group consisting of histamine receptor antagonists and purinergic agents to an individual in need of treatment thereof, wherein the compound alters properties of the mucus selected from the group consisting of rheological properties, hydrogen ion retention, hydrophobicity, changes in phospholipid content, sulfation, glycosylation, macromolecular assembly, surface tension, adhesivity, and transport properties.
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Accused Products
Abstract
The first aspect of the invention relates to a method of inducing changes in the cervical mucus of a person to achieve a contraceptive effect, and wherein the method involves administering to the person an effective amount of ebrotidine sufficient to achieve a contraceptive effect. The second aspect of the invention involves a method for treating atrophic vaginitis urinary incontinence and their associated signs and symptoms, in a person, the method involves administering to the person an effective mount of an agent sufficient to treatment of atrophic vaginitis, the agent being selected from a group consisting of stimulants or antagonists, purinergic receptors, a sodium ion update agents and an anion secretion inhibitors.
95 Citations
16 Claims
- 1. A method of affecting the amount of or properties of the cervical and vaginal mucosa comprising administering an effective amount of a composition comprising a compound selected from the group consisting of histamine receptor antagonists and purinergic agents to an individual in need of treatment thereof, wherein the compound alters properties of the mucus selected from the group consisting of rheological properties, hydrogen ion retention, hydrophobicity, changes in phospholipid content, sulfation, glycosylation, macromolecular assembly, surface tension, adhesivity, and transport properties.
Specification