Powdered human milk fortifier

• US 6,294,206 B1
• Filed: 03/21/2000
• Issued: 09/25/2001
• Est. Priority Date: 04/09/1999
• Status: Expired due to Term

• Current Assignee: Abbott Laboratories
• Original Assignee: Abbott Laboratories
• Inventors: Barrett-Reis, Bridget, Montalto, Michael B., Reynolds, Patricia A., OʼConnor, Deborah L.
• Primary Examiner(s): Pratt, Helen
• Application Number:
  US09/532,838
• Time in Patent Office: 553 Days
• Field of Search: 426/72, 426/73, 426/74, 426/801, 426/2
• US Class Current: 426/72
• CPC Class Codes: A23C 11/04 containing non-milk fats but no non-milk proteins A23C11/08, A23C11/10 take precedence
• CPC Class Codes: A23C 9/206 Colostrum; Human milk
• CPC Class Codes: A61P 3/02 Nutrients, e.g. vitamins, minerals
• CPC Class Codes: Y10S 426/801 Pediatric

Abstract

The invention relates to a powdered human milk fortifier comprising a protein component typically present in an amount of from about 24 wt/wt % to about 55 wt/wt % of the fortifier powder, and a fat component typically present in an amount of from about 1 wt/wt % to about 30 wt/wt % of the fortifier powder and a carbohydrate component present in a quantity of from about 15 wt/wt % to about 75 wt/wt % of the fortifier powder. Preferably, the powdered human milk fortifier is provided in a unit dose container which holds from about 0.5 gm to about 10 gm of powder. The instant invention also relates to a method of providing nutrition to preterm infants by adding a fortifier powder to human milk and administering the fortified human milk to a premature infant. The invention further provides a method of promoting growth of a premature infant by administering fortified human milk to a premature infant.

Claims

1. A powdered human milk fortifier comprising:

a. a protein component present in a quantity of from about 28 wt/wt % to about 42 wt/wt % of the powdered human milk fortifier,

b. a fat component present in a quantity of from about 5 wt/wt % to about 30 wt/wt % of the powdered human milk fortifier wherein said fat component further comprises a source of medium chain triglycerides,

c. a carbohydrate component present in a quantity of from about 28 wt/wt % to about 67 wt/wt % of the powdered human milk fortifier, and;

d. at least one source of insoluble calcium.

2. The powdered human milk fortifier according to claim 1 which further comprises at least one source of iron.

3. A method of providing supplemental nutrients to preterm ipfants comprising adding the powdered human milk fortifier according to claim 1 to human milk and administering a fortified human milk to a premature infant.

4. A method for promoting growth of a premature infant comprising administering fortified human milk to a premature infant, said fortified human milk comprises:

a. human milk, and

b. the powdered human milk fortifier according to claim 1.

5. The method of providing supplemental nutrients according to claim 3, in which about 0.5 gm to about 10 gm of said fortifier is administerd per day.

6. A powdered human milk fortifier comprising:

a. a protein component present in a quantity of from about 28 wt/wt % to about 36 wt/wt % of the powdered human milk fortifier,

b. a fat component present in a quantity of from about 5 wt/wt % to about 20 wt/wt % of the powdered human milk fortifier wherein said fat component further comprises a source of medium chain triglycerides,

c. a carbohydrate component present in a quantity of from about 44 wt/wt % to about 67 wt/wt % of the powdered human milk fortifier, and;

d. at least one source of insoluble calcium.

7. The powdered human milk fortifier according to claim 6 which further comprises at least one source of iron.

8. A method of providing supplemental nutrients to preterm infants comprising adding the powdered human milk fortifier according to claim 6 to human milk and administering a fortified human milk to a premature infant.

9. The method of providing supplemental nutrients according to claim 8, in which about 0.5 gm to about 10 gm of said fortifier is administered per day.

10. A method for promoting growth of a premature infant comprising administering fortified human milk to a premature infant, said fortified human milk comprises:

a. human milk, and

b. the powdered human milk fortifier according to claim 6.

11. A fortified human milk comprising:

a.) human milk, and

b.) from about 0.008 wt/vol % to about 0.05 wt/vol % of a powdered human milk fortifier which comprises;

i.) a protein component present in a quantity of from about 28 wt/wt % to about 55 wt/wt % of the powdered human milk fortifier,

ii.) a fat component p rsent in a quantity of from about 8wt/wt % to about 30 wt/wt % of the powdered human milk fortifier,

iii.) a carbohydrate component present in a quantity of from about 15 wt/wt % to about 75 wt/wt % of the powdered human milk fortifier, and

iv.) at least one source of insoluble calcium.

12. A method of providing supplemental nutrients to preterm infants comprising administering the fortified human milk according to claim 11 to a premature infant.

13. A method for promoting growth of a premature infant comprising administering the fortified human milk according to claim 11 to a premature infant.