Anti-fungal herbal formulation for treatment of human nails fungus and process thereof
First Claim
1. An antifungal composition for the treatment of human nails which comprises from 10-15% by weight of extract of walnut hull in acetone or alcohol or butanol wherein the extract of walnut hull has been partially fractionated, 20 to 30% by weight of pulverized roots of Nardostachys jatamansi or Vetiveria zizanioides or Catharanthus roseus, 5-10% by weight of polyols selected from propylene glycol, polyethylene glycol, and ethylene glycol, 5-10% by weight of fixed oil selected from sesame oil, mustard oil, and linseed oil 5-10%, 10-15% by weight of non-ionic emulsifiers selected from stearic acid, lanolin and vegetable wax, 15-20% by weight of thickening agent plasticizer selected from polyvinyl acetate, amyl acetate, and food grade gelatin and 20-25% by weight of base selected from nitrocellulose, kaolin and talc, based upon 100% weight of total antifungal composition.
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Abstract
The invention relates to an antifungal composition for the treatment of human nails containing extracts of walnut hull, pulverized roots of Nardostachys jatamansi or Vetiveria zizanioides or Catharanthus roseus, polyols, fixed oil, non-ionic emulsifiers, thickening agent plasticizer and base. The invention also relates to a process for the preparation of the above synergistic composition.
36 Citations
6 Claims
- 1. An antifungal composition for the treatment of human nails which comprises from 10-15% by weight of extract of walnut hull in acetone or alcohol or butanol wherein the extract of walnut hull has been partially fractionated, 20 to 30% by weight of pulverized roots of Nardostachys jatamansi or Vetiveria zizanioides or Catharanthus roseus, 5-10% by weight of polyols selected from propylene glycol, polyethylene glycol, and ethylene glycol, 5-10% by weight of fixed oil selected from sesame oil, mustard oil, and linseed oil 5-10%, 10-15% by weight of non-ionic emulsifiers selected from stearic acid, lanolin and vegetable wax, 15-20% by weight of thickening agent plasticizer selected from polyvinyl acetate, amyl acetate, and food grade gelatin and 20-25% by weight of base selected from nitrocellulose, kaolin and talc, based upon 100% weight of total antifungal composition.
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4. A process for the preparation of an antifungal composition for the treatment of human nails which comprises from 10-15% by weight of extract of walnut hull in acetone or alcohol or butanol wherein the extract of walnut hull has been partially fractionated, 20 to 30% by weight of pulverized roots of Nardostachys jatamansi or Vetiveria zizanioides or Catharanthus roseus, 5-10% by weight of polyols selected from propylene glycol, polyethylene glycol, and ethylene glycol, 5-10% by weight of fixed oil selected from sesame oil, mustard oil, and linseed oil 5-10%, 10-15% by weight of non-ionic emulsifiers selected from stearic acid, lanolin, and vegetable wax, 15-20% by weight of thickening agent plasticizer selected from polyvinyl acetate, amyl acetate, and food grade gelatin and 20-25% by weight of base selected from nitrocellulose, kaolin and talc, based upon 100% weight of total antifungal composition, said process comprising
(a) washing the walnut hulls of Juglans regia with water, air drying and extracting the said hulls at ambient temperature with acetone, butanol or alcohols, (b) making the extract solvent free by any known method and partially fractionating the said extract by chilling, (c) washing the roots of Nardostachys jatamansi or Vetiveria zizanioides or Catharanthus roseus with water and air drying and powdering the roots to ≦ - 80 microns to get pulverised material,
(d) heating a thickening agent plasticizer selected from polyvinyl acetate, food grade gelatin and amyl acetate at a temperature of up to 80°
C.,(e) adding a base selected from nitrocellulose, kaolin and talc for filling by stirring, and (f) adding a fixed oil selected from sesame oil, mustard oil, and linseed oil and a polyol selected from propylene glycol, polyethylene glycol, and ethylene glycol to the solution from step (e). - View Dependent Claims (5, 6)
- 80 microns to get pulverised material,
Specification